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Major Depressive Disorder clinical trials in South Carolina

8 studies for Major Depressive Disorder are looking for participants at sites in South Carolina.

Cities in South Carolina

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

  • Clinical Trials of South Carolina, Charleston
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Sep 25, 2026 · NCT06559306

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

  • Coastal Carolina Research Center, North Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

  • Medical University of South Carolina, Charleston
Recruiting
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

  • Coastal Carolina Research, North Charleston
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Aug 10, 2026 · NCT07592689

RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

  • Medical Univeristy of South Carolina, Charleston
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Jul 21, 2026 · NCT05977439

Mindfulness Training During Accelerated TMS for Depression

  • IOP, Charleston
  • Medical University of South Carolina (MUSC), Brain Stimulation Laboratory Institute of Psychiatry, Charleston
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 17, 2026 · NCT07369557

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

  • Lowcountry Center for Veterans Research, Charleston
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT07280065

Dosing rTMS for Depression Post-SCI

  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Recruiting
Ages 18 to 60 · All sexes · Updated Jan 14, 2026 · NCT05553353

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.