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Melanoma clinical trials in Tennessee

39 studies for Melanoma are looking for participants at sites in Tennessee.

Cities in Tennessee

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

  • Sarah Cannon Research Institute- Pharmacy, Nashville
  • SCRI Oncology Partners, Nashville
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07519655

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

  • Tennessee Oncology - Chattanooga, Chattanooga
  • University of Tennessee Medical Center, Knoxville
  • Sarah Cannon Research Institute (SCRI) Oncology Partners, Nashville
  • and 1 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06246916

DESTINY-PANTUMOUR04

  • Research Site, Nashville
RecruitingObservational study
Ages 18 to 130 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07124000

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • SCRI Oncology Partners, Nashville
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06172478

A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information

  • East Tennessee Childrens Hospital, Knoxville
  • Saint Jude Children's Research Hospital, Memphis
RecruitingPhase 2
Up to age 25 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT07621614

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06047379

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

  • Baptist Cancer Center, Bartlett
  • SCRI Oncology Partners, Nashville
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT05727904

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

  • Vanderbilt University/Ingram Cancer Center, Nashville
RecruitingPhase 3
Ages 75 and older ยท All sexes ยท Updated Sep 24, 2026 ยท NCT07068074

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 18, 2026 ยท NCT05267626

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1
Ages 18 to 80 ยท All sexes ยท Updated Sep 18, 2026 ยท NCT06398418

A Study of BI 3810944 in Patients With Advanced Cancer

  • Tennessee Oncology, PLLC - Elliston Place Plaza DDU, Nashville
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07224425

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

  • Sarah Cannon Research Institute Oncology Partners, Nashville
  • Vanderbilt-Ingram Cancer Institute, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 4, 2026 ยท NCT07287917

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

  • Sarah Cannon Research Institute-Tennessee Oncology, Nashville
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Sep 2, 2026 ยท NCT04913285

Project: Every Child for Younger Patients With Cancer

  • T C Thompson Children's Hospital, Chattanooga
  • East Tennessee Childrens Hospital, Knoxville
  • Saint Jude Children's Research Hospital, Memphis
  • and 2 more
RecruitingObservational study
Up to age 25 ยท All sexes ยท Updated Aug 25, 2026 ยท NCT02402244

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

  • Saint Jude Children's Research Hospital, Memphis
RecruitingPhase 1/2
12 Months โ€“ 30 Years ยท All sexes ยท Updated Aug 25, 2026 ยท NCT04851119

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Aug 17, 2026 ยท NCT04895709

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

  • Tennessee Oncology, PLLC, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Aug 14, 2026 ยท NCT06425926

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

  • Sarah Cannon Research Institute Oncology Partners (SCRI-Nashville), Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Aug 11, 2026 ยท NCT05592626

Phase 1/2 Study of Intravenous Injection of STX-003 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Aug 6, 2026 ยท NCT07751042

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  • Erlanger Health, Inc, Chattanooga
  • The West Clinic, Germantown
  • SCRI Oncology Partners, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Aug 5, 2026 ยท NCT06330064

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

  • Tennessee Oncology, Nashville
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Jul 28, 2026 ยท NCT06150664

Familial Investigations of Childhood Cancer Predisposition

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational study
All ages ยท All sexes ยท Updated Jun 17, 2026 ยท NCT03050268

A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1/2
Ages 18 to 70 ยท All sexes ยท Updated Jun 15, 2026 ยท NCT06940739

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

  • The Sarah Cannon Research Institute/Tennessee Oncology, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Jun 8, 2026 ยท NCT03947385

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

  • St. Jude Children's Research Hospital, Memphis
RecruitingPhase 1
Up to age 21 ยท All sexes ยท Updated May 19, 2026 ยท NCT04897321

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

  • Tennessee Oncology, Chattanooga
  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated May 15, 2026 ยท NCT05379985

Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

  • Vanderbilt-Ingram Cancer Center, Nashville
Recruiting
Ages 18 and older ยท All sexes ยท Updated May 6, 2026 ยท NCT07555210

Neoadjuvant Darovasertib in Primary Uveal Melanoma

  • SCRI Oncology Partners, Nashville
  • Vanderbilt Eye Institute, Nashville
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated May 6, 2026 ยท NCT07015190

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

  • SCRI Oncology Partners, Nashville
  • Vanderbilt-Ingram Cancer Center, Nashville
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Apr 20, 2026 ยท NCT06326411

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naรฏve Adult Patients With Metastatic Uveal Melanoma

  • The West Clinic, PLLC dba West Cancer Center, Germantown
  • University of Tennessee Medical Center, Knoxville
  • Sarah Cannon Research Institute, Nashville
  • and 1 more
RecruitingPhase 2/3
All ages ยท All sexes ยท Updated Apr 2, 2026 ยท NCT06581406

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Baptist Memorial Hospital and Cancer Center-Collierville, Collierville
  • Baptist Memorial Hospital and Cancer Center-Memphis, Memphis
  • Baptist Memorial Hospital for Women, Memphis
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Mar 17, 2026 ยท NCT06418204

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

  • University of Tennessee Medical Center, Knoxville
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Feb 25, 2026 ยท NCT05549297

Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

  • Vanderbilt-Ingram Cancer Center, Nashville
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Feb 13, 2026 ยท NCT04903119

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 136, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Nov 21, 2025 ยท NCT05914116

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

  • St. Jude Children's Research Hospital, Memphis
RecruitingObservational study
Up to age 18 ยท All sexes ยท Updated Nov 10, 2025 ยท NCT02775643

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Memphis
  • Massive Bio SYNERGY-AI site, Nashville
RecruitingObservational study
All ages ยท All sexes ยท Updated Oct 28, 2025 ยท NCT03452774

Storage and Research Use of Human Bio-specimens From Melanoma Patients and Clinical Testing for Assignment of Treatment

  • Vanderbitl-Ingram Cancer Center, Nashville
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Sep 19, 2025 ยท NCT01205815

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

  • Sarah Cannon Research Institute, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated May 18, 2025 ยท NCT05970497

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

  • Verdi Oncology Tennessee, Scri Oncology Partners, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Feb 13, 2025 ยท NCT05669430

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.