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Metastatic Cancer clinical trials in Florida
91 studies for Metastatic Cancer are looking for participants at sites in Florida.
Cities in Florida
- Tampa29 studies
- Orlando29 studies
- Jacksonville28 studies
- Miami24 studies
- Sarasota19 studies
- Gainesville7 studies
- Coral Springs6 studies
- Plantation6 studies
- Deltona5 studies
- West Palm Beach5 studies
- Cape Coral5 studies
- St. Petersburg4 studies
- Kendall4 studies
- Fort Lauderdale3 studies
- Port Charlotte3 studies
- Ocala3 studies
- Largo3 studies
- Town 'n' Country3 studies
- Port Saint Lucie3 studies
- Deerfield Beach3 studies
- Hollywood3 studies
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
- UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- and 6 more
RecruitingPhase 2
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
- Advent Health, Orlando
- Florida Cancer Specialists South, Port Charlotte
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
- Miami Cancer Institute, Miami
- Hematology Oncology Associates of the Treasure Coast, Port Saint Lucie
- Florida Cancer Specialists - South, Sarasota
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene
- UF Health Cancer Institute - Gainesville, Gainesville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
- AdventHealth Cancer Institute, Orlando
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
- Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05222620A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
- ALX Center 7, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091A Study of ASP3082 in Adults With Advanced Solid Tumors
- University of Florida, Davis Cancer Center, Gainesville
- Florida Cancer Specialist, Lake Mary
- Florida Cancer Specialists & Research Institute Sarasota, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors
- Florida Cancer Specialists, Sarasota
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05875168Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
- Mayo Clinic - Florida, Jacksonville
- AdventHealth Orlando, Orlando
- Moffitt Cancer Center, Tampa
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06943755Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
- UF Health Cancer Institute - Gainesville, Gainesville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05803382Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
- Florida Cancer Specialists, Bonita Springs
- Florida Cancer Specialists, Bradenton
- Comprehensive Hematology Oncology, Brandon
- and 19 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
- BRCR Global-Coral Springs, Coral Springs
- Mayo Clinic Florida, Jacksonville
- Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
- and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
- Florida Cancer Specialists, Bonita Springs
- Florida Cancer Specialists, Bradenton
- Florida Cancer Specialists, Cape Coral
- and 46 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
- Mayo Clinic Pharmacy, Jacksonville
- Mayo Clinic, Jacksonville
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
- Research Site, Altamonte Springs
- Research Site, Miami
- Research Site, Plantation
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06103864ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
- Mayo Clinic, Jacksonville
- Sylvester Comprehensive Cancer Center, Miami
- Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
- University of Miami, Coral Gables
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06911008A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
- AdventHealth Orlando, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
- AdventHealth Altamonte Springs, Altamonte Springs
- Clermont Oncology Center, Clermont
- Florida Oncology & Hematology, Fort Myers
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- Florida Cancer Specialists, Sarasota
- Moffitt Cancer Center and Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551A Study of LY4257496 in Participants With Cancer (OMNIRAY)
- Moffitt, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
- Omnicure Clinical Research, Doral
- Bioresearch Partner, Hialeah
- Florida Clinical Trials Group, Plantation
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07262619A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
- Broward Health Medical Center, Fort Lauderdale
- Florida Cancer Specialist- South, Fort Myers
- Baptist MD Anderson Cancer Center, Jacksonville
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
- Florida Cancer Specialists & Research Institute - Sarasota, Sarasota
- Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
- Sylvester Comprehensive Cancer Center - Miami, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
- Mayo Clinic Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07450859Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
- Mayo Clinic Pharmacy, Jacksonville
- Orlando Health Ambulatory Care Center, Orlando
- Orlando Health Cancer Institute, Orlando
- and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07227415A Study of KK2269 in Adult Participants With Solid Tumors
- Mayo Clinic Jacksonville, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06266299CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
- Clinical Study Site, Orlando
- Clinical Study Site, Sarasota
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07335497A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
- Florida Cancer Specialist, Sarasota
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
- UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
- UM Sylvester Comprehensive Cancer Center at Doral, Doral
- and 4 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04585958A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- Millennium Oncology Research Clinic, Hollywood
- University of Florida - Jacksonville, Jacksonville
- Miami Cancer Institute at Baptist Health, Inc., Miami
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
- University of Miami, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
- UF Health Cancer Institute - Gainesville, Gainesville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06311214AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
- Avenzo Therapeutics Recruiting Site, Orlando
- Avenzo Therapeutics Recruiting Site, Sarasota
- Avenzo Therapeutics Recruiting Site, Tampa
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343A Study of IDP-001 in Advanced or Metastatic Solid Tumors
- Florida Cancer Specialists, Sarasota
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07602842A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
- Mayo Clinic - Florida, Jacksonville
- Sarah Cannon Research Institute - Florida Cancer Specialists, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.