Home › Multiple Sclerosis › Massachusetts
Multiple Sclerosis clinical trials in Massachusetts
19 studies for Multiple Sclerosis are looking for participants at sites in Massachusetts.
Cities in Massachusetts
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
- Massachusetts General Hospital Cancer Center, Boston
- Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Dana Farber Cancer Institute, Boston
- University of Massachusetts Chan Medical Center, Worcester
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 10, 2026 · NCT07002034Dalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple Sclerosis
- MGH Institute of Health Professions, Boston
RecruitingPhase 3
Ages 25 to 75 · All sexes · Updated Nov 6, 2026 · NCT06136728A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
- TG Therapeutics Investigational Trial Site, Boston
- TG Therapeutics Investigational Trial Site, Burlington
- TG Therapeutics Investigational Trial Site, Norfolk
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06433752Efgartigimod for the Treatment of Acute Optic Neuritis
- Massachusetts Eye and Ear Infirmary, Boston
- Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT06453694A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
- Neurology Center of New England, Foxborough
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Oct 27, 2026 · NCT06782490iConquerMS™ - A Patient-Powered Research Network for Multiple Sclerosis
- Accelerated Cure Project, Waltham
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Oct 27, 2026 · NCT02486562Care in Multiple Sclerosis (MS)
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 to 29 · All sexes · Updated Oct 26, 2026 · NCT07011914Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
- Neurology Center of New England- Site Number : 8400164, Foxborough
RecruitingPhase 3
Ages 18 to 60 · All sexes · Updated Oct 13, 2026 · NCT07325292A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis
- Neuro Institute of New England P C, Foxborough
- Elliot Lewis MS Center, Wellesley
- U Mass Memorial Medical Center, Worchester
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Oct 13, 2026 · NCT07225504Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects
- Massachusetts General Hospital, Boston
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Oct 7, 2026 · NCT04699747Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis
- Beth Israel Deaconess Medical Center, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 11, 2026 · NCT04603196Molecular Imaging of NET Using [C-11]MRB-PET in MS
- Brigham MS Center, 60 Fenwood Road, Boston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 60 · All sexes · Updated Feb 2, 2026 · NCT03207464PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
- Brigham MS Center, 60 Fenwood Road, Boston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Jan 28, 2026 · NCT02649985Assessment of Synaptic Density in MS
- Brigham and Women's Hospital, Boston
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 60 · All sexes · Updated Jan 9, 2026 · NCT04634994Glucose Consumption in MS Using [F-18]FDG-PET
- Brigham & Women's Hospital, Boston
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Jan 9, 2026 · NCT07087106Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension
- UMass Boston, Boston
Recruiting
Ages 18 and older · All sexes · Updated Aug 22, 2025 · NCT06554340Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis
- Brigham and Women's Hospital, Boston
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Jun 6, 2025 · NCT06890923A Single-Center Study to Characterize the Safety and Efficacy of Ublituximab in Older Adults With Relapsing Forms of Multiple Sclerosis (RMS)
- Neurology Center of New England P.C., Foxborough
RecruitingObservational study
Ages 55 to 80 · All sexes · Updated Nov 18, 2024 · NCT06681623From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.