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Obesity clinical trials in California

99 studies for Obesity are looking for participants at sites in California.

Cities in California

Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight

  • Apex Clinical Research, San Diego
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07871409

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • University of California Irvine, Irvine
  • Artemis Institute for Clinical Research, LLC, San Diego
  • Diablo Clinical Research, Inc., Walnut Creek
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07351045

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

  • Research Site, Escondido
  • Research Site, Lincoln
  • Research Site, Walnut Creek
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07776509

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

  • University of California Irvine, Irvine
  • Orange County Research Center, Lake Forest
  • Ark Clinical Research, Long Beach
  • and 4 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07351058

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

  • Research Site, Glendale
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07511205

An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

  • San Diego State University, San Diego
  • UC San Diego Health, San Diego
Recruiting
Ages 18 and older ยท Women ยท Updated Nov 6, 2026 ยท NCT07792837

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes

  • Diablo Clinical Research - Flourish Research, Walnut Creek
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07685808

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

  • Peninsula Research Associates, Chula Vista
  • Desert Oasis Healthcare Medical Group, Palm Springs
  • Inland Empire Liver Foundation, Rialto
  • and 2 more
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07575399

A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity

  • Anaheim Clinical Trials, LLC, Anaheim
RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07876531

A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)

  • Probe Clinical Research Corporation, Riverside
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07823608

A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity

  • San Fernando Valley Health Institute, Canoga Park
  • Velocity Clinical Research - Los Angeles, Los Angeles
  • Headlands Research Sacramento, Sacramento
  • and 3 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07845500

Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes

  • Acclaim Clinical Research, San Diego
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07866066

A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes

  • Institute for Metabolic Research Los Angeles, Los Angeles
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07843485

A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)

  • Headlands Research California, LLC, Escondido
  • Prospective Research Innovations Inc., Rancho Cucamonga
  • Solace Clinical Research, Tustin
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07919678

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

  • San Fernando Valley Health Institute, Canoga Park
  • Headlands Research California, LLC, Escondido
  • ImmuniMet, LLC, Modesto
  • and 4 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07595549

A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes

  • Pacific Clinical Studies Inc., Los Alamitos
  • Los Angeles Institute for Metabolic Research, Los Angeles
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07881458

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

  • First OC Dermatology Research Inc, Fountain Valley
  • Center For Dermatology Clinical Research, Inc., Fremont
  • Metropolis Dermatology, Los Angeles
  • and 1 more
RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06857942

Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)

  • Loma Linda University School of Medicine, Loma Linda
  • Childrens Hospital of Los Angeles, Los Angeles
  • UCLA Mattel Children's Hospital, Los Angeles
  • and 2 more
RecruitingPhase 3
Ages 6 to 11 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07817875

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • San Fernando Valley Health Institute, Canoga Park
  • AMCR Institute, Escondido
  • NorCal Medical Research, Inc, Greenbrae
  • and 6 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • Irvine Clinical Research, Irvine
  • Scripps Whittier Diabetes Institute, La Jolla
  • EndoTrials Center for Clinical Research, La Mesa
  • and 5 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07392190

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

  • Ark Clinical Research - Fountain Valley, Fountain Valley
  • Wolverine Clinical Trials, Santa Ana
  • Encompass Clinical Research, Spring Valley
  • and 1 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07353931

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Smart Cures Clinical Research, Anaheim
  • Cedars-Sinai Medical Center, Beverly Hills
  • United Medical Doctors - Los Alamitos, Los Alamitos
  • and 1 more
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06937099

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

  • Ark Clinical Research, Long Beach
  • Collaborative Neuroscience Research, LLC, Los Alamitos
  • Artemis Institute for Clinical Research, Riverside
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07369011

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Smart Cures Clinical Research, Anaheim
  • Cedars-Sinai Medical Center, Beverly Hills
  • United Medical Doctors - Los Alamitos, Los Alamitos
  • and 1 more
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06937086

Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication

  • UCLA Center for Human Nutrition, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07806838

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • Loma Linda University School of Medicine, Loma Linda
  • Childrens Hospital of Los Angeles, Los Angeles
  • UCLA Mattel Children's Hospital, Los Angeles
  • and 2 more
RecruitingPhase 3
Ages 6 to 17 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06672549

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

  • Wolverine Clinical Trials, Santa Ana
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06897475

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • Thrive Clinical Research Group, Glendora
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 3, 2026 ยท NCT07783802

Comparing the Extent to Which Maridebart Cafraglutide is Made Available in the Body of Participants Living With Overweight or Obesity After Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA)

  • Catalina Research Institute LLC (CRI) - Montclair, Montclair
RecruitingPhase 1
Ages 18 to 70 ยท All sexes ยท Updated Nov 2, 2026 ยท NCT07908316

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

  • Research Site, Escondido
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 30, 2026 ยท NCT07784725

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • National Heart Institute, Beverly Hills
  • Valley Clinical Trials, LLC dba Flourish Research, Covina
  • National Institute of Clinical Research, Huntington Beach
  • and 9 more
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT07037459

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Bakersfield
  • Research Site, Gardena
  • Research Site, Lincoln
  • and 2 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 28, 2026 ยท NCT07784270

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

  • John Muir Health - Concord /ID# 282469, Concord
  • Aurora FDRC Inc. /ID# 282494, Costa Mesa
  • NorCal Medical Research /ID# 283117, Greenbrae
  • and 7 more
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 27, 2026 ยท NCT07752979

Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity

  • Exponent Menlo Park, Menlo Park
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Oct 26, 2026 ยท NCT07776678

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

  • Profound Research, Oceanside
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 26, 2026 ยท NCT07837973

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Escondido
  • ACCOMPLISH-2 Research Site, Fountain Valley
  • ACCOMPLISH-2 Research Site, La Jolla
  • and 4 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 ยท All sexes ยท Updated Oct 20, 2026 ยท NCT07654374

Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery

  • University of California Irvine Medical Center, Orange
RecruitingPhase 4
Ages 18 to 70 ยท All sexes ยท Updated Oct 19, 2026 ยท NCT05975580

Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

  • Diablo Clinical Research, Inc., Walnut Creek
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Oct 19, 2026 ยท NCT07607587

A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide Medication

  • PAREXEL Glendale/LA EPCU, Glendale
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Oct 16, 2026 ยท NCT07868354

A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide Medication

  • PAREXEL Glendale/LA EPCU, Glendale
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Oct 16, 2026 ยท NCT07855133

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.