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Obesity clinical trials in Tennessee

38 studies for Obesity are looking for participants at sites in Tennessee.

Cities in Tennessee

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

  • Holston Medical Group - Bristol /ID# 282045, Bristol
  • New Phase Research & Development /ID# 282131, Knoxville
  • Summit Medical Group- Halls Family Physicians /ID# 282435, Knoxville
  • and 1 more
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT07752979

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

  • M3 Wake Research Chattanooga, Chattanooga
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07533175

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

  • LifeDoc Health, Memphis
RecruitingPhase 3
Ages 8 to 18 ยท All sexes ยท Updated Sep 30, 2026 ยท NCT07253285

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

  • AMR Clinical, Nashville
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07837973

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Gastroenterology Center Of The Midsouth, Cordova
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06937099

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • Vanderbilt Health One Hundred Oaks, Nashville
RecruitingPhase 3
Ages 6 to 17 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06672549

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Gastroenterology Center Of The Midsouth, Cordova
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06937086

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Franklin
  • Research Site, Jackson
  • Research Site, Knoxville
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07784270

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • Stern Cardiovascular Foundation Inc, Germantown
  • Accellacare of Knoxville, Knoxville
  • Cardiovascular Research of Knoxville North Knoxville Medical Center, Powell
  • and 1 more
RecruitingPhase 3
Ages 45 to 99 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07037433

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

  • AMR Clinical, Nashville
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07321886

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

  • Quality Medical Research, Nashville
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07589608

Transition to Ambulatory Bariatric Surgery (TABS) Trial

  • Vanderbilt University Medical Center, Nashville
Recruiting
Ages 25 to 55 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT07011628

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

  • AURORA-1 Clinical Site, Memphis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07743463

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Memphis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07743450

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • Apex Research Foundation, LLC, Jackson
  • The Jackson Clinic PA, Jackson
  • Parkway Cardiology Associates, Oak Ridge
  • and 2 more
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07037459

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • Innovative Clinical Research, Clarksville
  • Clinical Research Associates, Nashville
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07351045

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Nashville
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT07654374

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

  • Quality Medical Research, Nashville
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 8, 2026 ยท NCT06143956

Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

  • Kailea Clinical Site, Memphis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07284901

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

  • New Phase Research and Development, Knoxville
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07684235

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

  • Kailera Clinical Site, Chattanooga
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07284875

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Sep 1, 2026 ยท NCT05972564

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

  • Research Site, Kingsport
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 25, 2026 ยท NCT07784725

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  • Balad Hlth Sys-Welmont CardCVA, Greeneville
  • The Jackson Clinic, PA, Jackson
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 18, 2026 ยท NCT07567001

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

  • ACCOMPLISH-1 Research Site, Knoxville
RecruitingPhase 3
Ages 18 to 79 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07654361

Atomoxetine in Melanocortin Obesity Syndrome

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 2
Ages 6 and older ยท All sexes ยท Updated Aug 7, 2026 ยท NCT06899178

A Study to Improve Skeletal Muscle in Veterans With HIV

  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
Recruiting
Ages 20 to 80 ยท Men ยท Updated Jun 26, 2026 ยท NCT06845046

Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

  • Holston Medical Group_Bristol, Bristol
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Jun 25, 2026 ยท NCT07607587

Daily Eating Patterns for Total Health Study

  • Healthy Eating and Activity Laboratory, Knoxville
Recruiting
Ages 25 to 60 ยท All sexes ยท Updated Jun 15, 2026 ยท NCT06455995

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

  • MBX Biosciences Investigational Site, Knoxville
RecruitingPhase 1
Ages 18 to 65 ยท All sexes ยท Updated Jun 9, 2026 ยท NCT07142707

EBT Fruit and Vegetable Prescription

  • Cherokee Health Systems, Dameron Avenue Pedatrics, Knoxville
RecruitingHealthy volunteers welcome
Ages 4 to 10 ยท All sexes ยท Updated Jun 9, 2026 ยท NCT05028205

Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

  • St. Jude Children's Research Hospital, Memphis
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Jun 4, 2026 ยท NCT07228741

Metabolic Effects of Angiotensin-(1-7)

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1
Ages 18 to 60 ยท All sexes ยท Updated May 22, 2026 ยท NCT02646475

Sympathetic Mechanisms in Obesity-Crossover Design

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 1/2
Ages 18 to 65 ยท All sexes ยท Updated Feb 27, 2026 ยท NCT05312892

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

  • Vanderbilt University Medical Center (Part C only), Nashville
RecruitingPhase 1/2Healthy volunteers welcome
Ages 12 to 65 ยท All sexes ยท Updated Dec 22, 2025 ยท NCT06239116

Tirzepatide in PWS, HO and GNSO

  • Vanderbilt University Medical Center, Nashville
RecruitingPhase 4
Ages 18 to 26 ยท All sexes ยท Updated Sep 16, 2025 ยท NCT06901245

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

  • University of Tennessee Medical Center, Knoxville
RecruitingObservational study
Ages 18 to 45 ยท Women ยท Updated Sep 10, 2025 ยท NCT06802861

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.