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Osteosarcoma clinical trials in St. Louis, MO

10 studies for Osteosarcoma are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 12 to 39 · All sexes · Updated Sep 29, 2026 · NCT04616560

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

RecruitingPhase 1/2
  • Cardinal Glennon Children's Medical Center, St Louis
Up to age 30 · All sexes · Updated Sep 3, 2026 · NCT06541262

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

RecruitingPhase 1/2
  • Cardinal Glennon Children's Medical Center, St Louis
Up to age 26 · All sexes · Updated Sep 3, 2026 · NCT06465199

Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma

RecruitingPhase 1/2
  • Washington University in St. Louis, St Louis
Ages 12 to 40 · All sexes · Updated Sep 3, 2026 · NCT07725380

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Washington University School of Medicine, St Louis
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

RecruitingPhase 3
  • Cardinal Glennon Children's Medical Center, St Louis
  • Washington University School of Medicine, St Louis
  • Mercy Hospital Saint Louis, St Louis
Up to age 50 · All sexes · Updated Aug 25, 2026 · NCT05235165

SPEARHEAD-3 Pediatric Study

RecruitingPhase 1/2
  • Washington University, St Louis
Ages 2 to 21 · All sexes · Updated Aug 11, 2026 · NCT05642455

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

RecruitingPhase 1/2
  • Washington University Medical Center, St Louis
Up to age 30 · All sexes · Updated Aug 3, 2026 · NCT06239272

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

RecruitingPhase 2
  • Washington University in St. Louis, St Louis
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT04040205

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

RecruitingObservational study
  • Washington University School of Medicine, St Louis
All ages · All sexes · Updated May 18, 2026 · NCT01790152

Osteosarcoma trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.