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Overweight clinical trials in Massachusetts

25 studies for Overweight are looking for participants at sites in Massachusetts.

Cities in Massachusetts

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

  • Brigham and Women's Hospital Diabetes Program, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • Boston Children's Hospital, Boston
RecruitingPhase 3
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

  • Knownwell, Needham
  • Lucida Clinical Trials, New Bedford
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • Brigham and Women's Hospital Diabetes Program, Boston
  • MedVadis Research Corporation, Waltham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, North Dartmouth
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

  • Skylight Health Research - Burlington, Burlington
  • Care Access - Quincy, Quincy
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

  • Care Access - Quincy, Quincy
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • Brigham and Womens Hospital, Boston
  • Btc of New Bedford, New Bedford
RecruitingPhase 3
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • Boston Medical Center, Boston
  • Knownwell, Needham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression

  • Massachusetts General Hospital, Boston
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Sep 11, 2026 · NCT07699445

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Methuen
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

  • Knownwell, Needham
  • Lucida Clinical Trials, New Bedford
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

  • Kailera Clinical Site, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284901

Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity

  • Exponent Boston, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07776678

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

  • ACCOMPLISH-1 Research Site, Methuen
  • ACCOMPLISH-1 Research Site, Needham
RecruitingPhase 3
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care

  • Tufts Medical Center, Boston
  • Tufts University, Boston
Recruiting
Ages 12 to 17 · All sexes · Updated Jul 21, 2026 · NCT07717658

Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food

  • Cambridge Health Alliance, Sommerville
Recruiting
Ages 18 to 60 · All sexes · Updated Jul 16, 2026 · NCT06988462

Time Restricted Eating (TRE) in Bipolar Disorder

  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 65 · All sexes · Updated Jun 15, 2026 · NCT07211217

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

  • Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 18 to 65 · All sexes · Updated Dec 24, 2025 · NCT05799222

Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

  • Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 10, 2025 · NCT06069622

International Weight Control Registry

  • Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 19, 2024 · NCT04907396

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.