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Parkinson's Disease clinical trials in Massachusetts
21 studies for Parkinson's Disease are looking for participants at sites in Massachusetts.
Cities in Massachusetts
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
- Site-071, Boston
- Site-004, Foxborough
RecruitingPhase 2/3
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT06976268GBPDC: Gut-Brain in PD Consortium Master Protocol
- Massachusetts General Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease
- Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Sep 21, 2026 · NCT07005180A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
- Beth Israel Deaconess Medical Center (Site #211), Boston
RecruitingPhase 2
Ages 30 to 80 · All sexes · Updated Sep 10, 2026 · NCT07432958Parkinson's Foundation PD GENEration Genetic Registry
- Massachusetts General Hospital (MGH), Boston
- Beth Israel Deaconess Medical Center (BIDMC), Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
- Boston Medical Center, Boston
RecruitingObservational study
Ages 45 to 75 · All sexes · Updated Sep 4, 2026 · NCT07330258A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
- Massachusetts General Hospital, Boston
RecruitingPhase 3
Ages 50 to 85 · All sexes · Updated Sep 3, 2026 · NCT07174310A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
- Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 2
Ages 40 to 80 · All sexes · Updated Aug 28, 2026 · NCT06680830A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease
- Boston University Center for Neurorehabilitation, Boston
Recruiting
Ages 40 and older · All sexes · Updated Aug 24, 2026 · NCT07705373A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
- Tufts Medical Center - Neurology, Boston
- Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 3
Ages 45 to 75 · All sexes · Updated Aug 4, 2026 · NCT06944522PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
- Boston University, Boston
- Massachusetts General Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
- Massachusetts General Hospital (Neurology), Boston
RecruitingPhase 2
Ages 45 to 75 · All sexes · Updated Jun 29, 2026 · NCT06285643Natural History Study of Synucleinopathies
- Beth Israel Deaconess Medical Center, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT01799915Dance and Energy Expenditure Among Adults With Parkinson's
- Northeastern University, Boston
RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Apr 13, 2026 · NCT06425731High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease
- Massachusetts Institute of Technology, Cambridge
Recruiting
Ages 45 to 90 · All sexes · Updated Mar 31, 2026 · NCT05268887Cortical-Basal Ganglia Speech Networks
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Mar 25, 2026 · NCT04286308Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons
- Massachusetts General Hospital, Boston
RecruitingPhase 1
Ages 45 to 80 · All sexes · Updated Mar 25, 2026 · NCT06687837Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients
- Boston University, Boston
- Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Mar 9, 2026 · NCT07455760PET Imaging Evaluation of [11C]SY08
- MGH, Charlestown
RecruitingEarly phase 1Healthy volunteers welcome
Ages 50 to 80 · All sexes · Updated Dec 24, 2025 · NCT06098612Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
- Massachusetts Eye and Ear Infirmary, Boston
RecruitingHealthy volunteers welcome
All ages · All sexes · Updated Dec 2, 2025 · NCT05317390Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease
- Harvard Science and Engineering Complex, Allston
- Boston University Sargent College of Health and Rehabilitation Sciences, Boston
Recruiting
Ages 18 to 90 · All sexes · Updated Jul 18, 2025 · NCT06602544From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.