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Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

RecruitingHealthy volunteers welcome

Who can join

All ages · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion criteria:

1. Males and females of diverse racial and ethnic backgrounds, with age across the lifespan;
2. Patients will have at least one of the forms of dystonia, including focal dystonia (e.g., laryngeal, cervical, oromandibular, blepharospasm, focal hand, musicians), segmental dystonia, or generalized dystonia;
3. Patients will have other movement disorders (Parkinson's disease, essential tremor, dyskinesia, myoclonus) and other non-neurological conditions (tic disorders, torticollis, ulnar nerve entrapments, temporomandibular disorders, dysphonia) that mimic dystonic symptoms.

Exclusion criteria:

1. Patients who are incapable of giving informed consent;
2. Patients who are unable to undergo brain MRI due to the presence of certain tattoos and ferromagnetic objects in their bodies (e.g., implanted stimulators, surgical clips, prosthesis, artificial heart valve) that cannot be removed or due to pregnancy or breastfeeding at the time of the study.

About the study

This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.

What is being tested

Sponsor: Massachusetts Eye and Ear Infirmary · Participants: 1,000 · Started: Jun 1, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05317390

Locations in the U.S.

MassachusettsMassachusetts Eye and Ear Infirmary, Boston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.