Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
RecruitingHealthy volunteers welcome
Who can join
All ages · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion criteria: 1. Males and females of diverse racial and ethnic backgrounds, with age across the lifespan; 2. Patients will have at least one of the forms of dystonia, including focal dystonia (e.g., laryngeal, cervical, oromandibular, blepharospasm, focal hand, musicians), segmental dystonia, or generalized dystonia; 3. Patients will have other movement disorders (Parkinson's disease, essential tremor, dyskinesia, myoclonus) and other non-neurological conditions (tic disorders, torticollis, ulnar nerve entrapments, temporomandibular disorders, dysphonia) that mimic dystonic symptoms. Exclusion criteria: 1. Patients who are incapable of giving informed consent; 2. Patients who are unable to undergo brain MRI due to the presence of certain tattoos and ferromagnetic objects in their bodies (e.g., implanted stimulators, surgical clips, prosthesis, artificial heart valve) that cannot be removed or due to pregnancy or breastfeeding at the time of the study.
About the study
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
What is being tested
- DystoniaNet-based diagnosis of isolated dystonia (diagnostic test)
Sponsor: Massachusetts Eye and Ear Infirmary · Participants: 1,000 · Started: Jun 1, 2022
Contact the study team
- Kristina Simonyan, MD, PhD · Phone: 617-573-6016
Official record on ClinicalTrials.gov — NCT05317390
Locations in the U.S.
| Massachusetts | Massachusetts Eye and Ear Infirmary, Boston |
Conditions
- Dystonia
- Parkinson's Disease
- Essential Tremor
- Dyskinesias
- Myoclonus
- Torticollis
- Temporomandibular Disorders
- Dysphonia
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.