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Primary Progressive Aphasia clinical trials recruiting in the U.S.

18 studies for Primary Progressive Aphasia are recruiting participants at sites across the United States.

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Recently updated studies

Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

RecruitingHealthy volunteers welcome
Ages 50 to 80 · All sexes · Updated Sep 9, 2026 · NCT03887481

Remotely-supervised Neuromodulation in PPA

Recruiting
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07260253

Biofluid Research on Age-Related or Inherited Neurodegeneration

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07798700

Propranolol in Primary Progressive Aphasia

RecruitingEarly phase 1
Ages 50 and older · All sexes · Updated Jul 17, 2026 · NCT06066710

Stimulating the Aging Brain Using Brain and Sensory Stimulation

Recruiting
Ages 45 and older · All sexes · Updated Jun 16, 2026 · NCT07650188

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

RecruitingHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jun 10, 2026 · NCT05741853

Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia

RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06511752

Communication Bridge 3 Study

RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Jun 1, 2026 · NCT06191198

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

RecruitingPhase 2Healthy volunteers welcome
Ages 50 to 90 · All sexes · Updated May 5, 2026 · NCT05386394

The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech

RecruitingObservational study
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT03313011

Intervention for Communication Quality of Life in Primary Progressive Aphasia

Recruiting
Ages 40 and older · All sexes · Updated Apr 21, 2026 · NCT07219680

Language in Primary Progressive Aphasia

RecruitingObservational study
All ages · All sexes · Updated Feb 27, 2026 · NCT00537004

UPenn Observational Research Repository on Neurodegenerative Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT04715399

Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 12, 2025 · NCT01818661

STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners

RecruitingHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Oct 27, 2025 · NCT06613204

Enhancing Language Function in Aphasia

RecruitingHealthy volunteers welcome
Ages 21 to 80 · All sexes · Updated Dec 9, 2024 · NCT05443633

Enhancing Language Function in Primary Progressive Aphasia

Recruiting
Ages 45 to 80 · All sexes · Updated Nov 29, 2024 · NCT04920318

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.