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Prostate Cancer clinical trials in Massachusetts
63 studies for Prostate Cancer are looking for participants at sites in Massachusetts.
Cities in Massachusetts
The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
RecruitingHealthy volunteers welcome
Ages 55 to 69 · Men · Updated Nov 13, 2026 · NCT05926102Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
- Lahey Clinic, Burlington
- Lahey Clinic Peabody, Peabody
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03866382Prostate Cancer Genetic Risk Evaluation and Screening Study
- Massachusetts General Hospital, Boston
RecruitingObservational study
Ages 35 and older · Men · Updated Nov 10, 2026 · NCT05129605Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence
- Massachusetts General Hospital, Boston
RecruitingPhase 4
Ages 18 and older · Men · Updated Nov 5, 2026 · NCT07569926A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
- Massachusetts General Hospital, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06465069A Study of LY4257496 in Participants With Cancer (OMNIRAY)
- Massachusetts General Hospital, Boston
- Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07114601Distance-Based Exercise to Preserve Function and Prevent Disability
- Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07059884Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
- Dana-Farber Cancer Institute at Foxborough, Foxborough
- Dana Farber-Merrimack Valley, Methuen
- Dana-Farber/Brigham and Women's Cancer Center at Milford Regional, Milford
- and 2 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06632977Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer
- Dana Farber Mass General Brigham Cancer Care Inc, Boston
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT06800313A Study of JNJ-101556143 in Participants With Metastatic Prostate Cancer
- Greater Boston Urology, Plymouth
RecruitingPhase 2
Ages 18 and older · Men · Updated Nov 3, 2026 · NCT07832292A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer
- Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · Men · Updated Nov 2, 2026 · NCT07581184A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
- Beth Israel Deaconess Medical Center ( Site 0043), Boston
- Dana Farber Cancer Institute ( Site 0012), Boston
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 30, 2026 · NCT06925737Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT
- Dana Farber Cancer Institute, Boston
- Brigham and Womens Hospital, Boston
RecruitingPhase 1
Ages 18 and older · Men · Updated Oct 29, 2026 · NCT06062745Precision-Based Genomics in Prostate Cancer
- Dana Farber Cancer Institute, Boston, MA, Boston
RecruitingObservational study
Ages 18 to 120 · Men · Updated Oct 26, 2026 · NCT04706663A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
- Mass General Hospital, Boston
RecruitingPhase 1
Ages 18 and older · Men · Updated Oct 23, 2026 · NCT07570979Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
- Dana-Farber/Brigham and Women's Cancer Center at Milford Regional, Milford
- and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 23, 2026 · NCT05946213Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
- Research Site, Boston
RecruitingPhase 1/2
Ages 18 to 130 · Men · Updated Oct 22, 2026 · NCT07181161Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy
- Massachsuetts General Hospital, Boston
RecruitingObservational study
Ages 18 and older · Men · Updated Oct 20, 2026 · NCT01961713A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
- Research Site, Boston
RecruitingPhase 1
Ages 18 and older · Men · Updated Oct 16, 2026 · NCT06879041Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
- Massachusetts General Hospital, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 15, 2026 · NCT06239194Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
- Beth Israel Deaconess Med Center, Boston
- Dana Farber Cancer Institute, Boston
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Oct 15, 2026 · NCT06855277A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
- Research Site, Plymouth
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 14, 2026 · NCT06952803FOG-001 in Locally Advanced or Metastatic Solid Tumors
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 7, 2026 · NCT05919264Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
- Research Site, Boston
RecruitingPhase 1/2
Ages 18 to 130 · All sexes · Updated Oct 5, 2026 · NCT05417594The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial
- Dana Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06496256Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes
- Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07729150Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
- Harvard Medical School-Massachusetts General Hospital, Boston
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236A Study in Patients With Metastatic Castration-Resistant Prostate Cancer
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07719361Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
- Dana Farber Cancer Institute, Boston
- Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 2/3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06780670CV CARE: CardioVascular Care in PC Patients
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT06202820Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial
- Beth Israel Deaconess Medical Center, Boston
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT06040125Serial MRI Scans During Radiation Therapy
- Brigham and Women Hospital, Boston
- Dana Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04188535Prostate Active Surveillance Study
- Beth Israel Deaconess Medical Center/Harvard Medical School, Boston
RecruitingObservational study
Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide
- Dana Farber Cancer Institute, Boston
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT06844383Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
- Brigham and Women's Hospital, Boston
RecruitingPhase 2
Ages 40 and older · Men · Updated Aug 17, 2026 · NCT06957691Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
- Dana-Farber Cancer Institute / Beth Israel Deaconess Medical Center, Boston
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 14, 2026 · NCT04812366A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
- Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · Men · Updated Aug 10, 2026 · NCT06067841RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
- Dana-Farber Cancer Institute at Foxborough, Foxborough
RecruitingPhase 2
Ages 18 and older · Men · Updated Jul 30, 2026 · NCT05765500Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy
- Dana Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · Men · Updated Jul 29, 2026 · NCT05327465From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.