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Prostate Cancer clinical trials in Boston, MA
56 studies for Prostate Cancer are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.
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The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
RecruitingHealthy volunteers welcome
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Prostate Cancer Genetic Risk Evaluation and Screening Study
RecruitingObservational study
- Massachusetts General Hospital, Boston
Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence
RecruitingPhase 4
- Massachusetts General Hospital, Boston
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
RecruitingPhase 1
- Massachusetts General Hospital, Boston
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
RecruitingPhase 1
- Massachusetts General Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Distance-Based Exercise to Preserve Function and Prevent Disability
Recruiting
- Dana-Farber Cancer Institute, Boston
Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer
RecruitingPhase 1/2
- Dana Farber Mass General Brigham Cancer Care Inc, Boston
A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer
RecruitingPhase 1
- Dana-Farber Cancer Institute, Boston
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
RecruitingPhase 3
- Beth Israel Deaconess Medical Center ( Site 0043), Boston
- Dana Farber Cancer Institute ( Site 0012), Boston
Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT
RecruitingPhase 1
- Dana Farber Cancer Institute, Boston
- Brigham and Womens Hospital, Boston
Precision-Based Genomics in Prostate Cancer
RecruitingObservational study
- Dana Farber Cancer Institute, Boston, MA, Boston
A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
RecruitingPhase 1
- Mass General Hospital, Boston
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
RecruitingPhase 3
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
RecruitingPhase 1/2
- Research Site, Boston
Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy
RecruitingObservational study
- Massachsuetts General Hospital, Boston
A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
RecruitingPhase 1
- Research Site, Boston
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
- Massachusetts General Hospital, Boston
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
RecruitingPhase 3
- Beth Israel Deaconess Med Center, Boston
- Dana Farber Cancer Institute, Boston
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
RecruitingPhase 1/2
- Research Site, Boston
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
Barrigel® PPRT (Post-Prostatectomy Radiation Therapy) Trial
Recruiting
- Dana Farber Cancer Institute, Boston
Reduce HEAT: A Randomized Trial of Wearable Thermal Devices for ADT-Induced Hot Flashes
Recruiting
- Dana-Farber Cancer Institute, Boston
Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
RecruitingPhase 1
- Harvard Medical School-Massachusetts General Hospital, Boston
A Study in Patients With Metastatic Castration-Resistant Prostate Cancer
RecruitingPhase 1
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
RecruitingPhase 2/3
- Dana Farber Cancer Institute, Boston
- Beth Israel Deaconess Medical Center, Boston
CV CARE: CardioVascular Care in PC Patients
Recruiting
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial
Recruiting
- Beth Israel Deaconess Medical Center, Boston
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Serial MRI Scans During Radiation Therapy
Recruiting
- Brigham and Women Hospital, Boston
- Dana Farber Cancer Institute, Boston
Prostate Active Surveillance Study
RecruitingObservational study
- Beth Israel Deaconess Medical Center/Harvard Medical School, Boston
A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide
RecruitingPhase 2
- Dana Farber Cancer Institute, Boston
Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
RecruitingPhase 2
- Brigham and Women's Hospital, Boston
Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
RecruitingPhase 2
- Dana-Farber Cancer Institute / Beth Israel Deaconess Medical Center, Boston
A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
RecruitingPhase 1
- Dana-Farber Cancer Institute, Boston
RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
RecruitingPhase 2
- Brigham and Women's Hospital, Boston
- Dana-Farber Cancer Institute, Boston
Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy
Recruiting
- Dana Farber Cancer Institute, Boston
PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.
RecruitingPhase 3
- Dana-Farber Cancer Institute, Boston
Jump: MR Simulation For Radiation Therapy Master Protocol
Recruiting
- Brigham and Women Hospital, Boston
- Dana Farber Cancer Institute, Boston
Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
RecruitingPhase 1
- Dana Farber Cancer Institute, Boston
Androgen-responsive POSLUMA-guided Intra-prostatic Boost
RecruitingPhase 2
- Brigham and Women's Hospital, Boston
- Dana Farber Cancer Institute, Boston
Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)
RecruitingPhase 3
- Brigham and Women's Hospital, Boston
- Brigham and Women's Faulkner Hospital, Boston
International Registry for Men With Advanced Prostate Cancer (IRONMAN)
RecruitingObservational study
- Dana-Farber Cancer Institute, Boston
Flotufolastat F 18 PET in Men With Very Low PSA Recurrence
RecruitingObservational study
- Massachusetts General Hospital, Boston
- Dana Farber Cancer Institute, Boston
Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
RecruitingObservational studyHealthy volunteers welcome
- Massachusetts General Hospital, Boston
Clinical Trial of Approaches to Prostate Cancer Surgery
Recruiting
- Beth Israel Deaconess Medical Center (BIDMC), Boston
Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer
RecruitingPhase 1/2
- Dana-Farber Cancer Institute, Boston
This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors
RecruitingPhase 1
- Dana Farber Cancer Institute, Boston
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Massachusetts General Hospital, Boston
Study of AZD0754 in Participants With Metastatic Prostate Cancer
RecruitingPhase 1/2
- Research Site, Boston
- Research Site, Boston
Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan
RecruitingPhase 4
- Dana Farber Cancer Institute, Boston
- Brigham and Womens Hospital, Boston
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
RecruitingPhase 4
- Massachussets General Hospital, Boston
MRI Guided Prostate Biopsy
Recruiting
- Brigham and Women's Hospital, Boston
Stereotactic Magnetic Resonance Guided Radiation Therapy
Recruiting
- Brigham & Women's Hospital, Boston
- Dana Farber Cancer Institute, Boston
Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
RecruitingHealthy volunteers welcome
- Massachusetts General Hospital, Boston
- Brigham and Women's Hospital, Boston
Comprehensive Outcomes for After Cancer Health
RecruitingHealthy volunteers welcome
- Dana Farber Cancer Institute, Boston
ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer
RecruitingObservational study
- Massachusetts General Hospital, Boston
About Prostate Cancer
Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.
More about Prostate Cancer on MedlinePlus
Prostate Cancer trials in other cities
- New York City, NY101 studies
- Houston, TX73 studies
- Los Angeles, CA64 studies
- Seattle, WA45 studies
- St. Louis, MO45 studies
- Chicago, IL45 studies
- Baltimore, MD45 studies
- San Francisco, CA44 studies
- Philadelphia, PA41 studies
- Nashville, TN40 studies
- Washington, DC39 studies
- Dallas, TX39 studies
Other studies in Boston
- Breast Cancer110 studies
- Cancer (all types)90 studies
- Non-Small Cell Lung Cancer87 studies
- Lung Cancer63 studies
- Colorectal Cancer62 studies
- Ovarian Cancer62 studies
- Metastatic Cancer61 studies
- Endometrial Cancer51 studies
- Depression50 studies
- Heart Failure46 studies
- Multiple Myeloma45 studies
- Acute Myeloid Leukemia44 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.