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Prostate Cancer clinical trials in Nebraska

28 studies for Prostate Cancer are looking for participants at sites in Nebraska.

Cities in Nebraska

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Nebraska Medicine-Bellevue, Bellevue
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT03866382

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Urology Cancer Center, PC, Omaha
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • Oncology Hematology West P.C. dba Nebraska Cancer Specialists ( Site 0026), Omaha
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

  • Nebraska Cancer Specialists, Omaha
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer

  • University of Nebraska Medical Center, Omaha
RecruitingPhase 2
Ages 30 and older · Men · Updated Sep 21, 2026 · NCT07234981

A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer

  • XCancer, Omaha
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07581184

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • University of Nebraska Medical Center Buffet Cancer Center, Omaha
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

  • XCancer Omaha LLC, Omaha
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • Nebraska Medicine-Bellevue, Bellevue
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • CHI Health Saint Francis, Grand Island
  • CHI Health Good Samaritan, Kearney
  • Alegent Health Immanuel Medical Center, Omaha
  • and 2 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

  • Research Site, Omaha
RecruitingPhase 1/2
Ages 18 to 99 · Men · Updated Aug 27, 2026 · NCT07590934

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

  • Research Site, Omaha
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 26, 2026 · NCT07611110

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

  • XCancer Omaha, Omaha
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

  • Nebraska Cancer Specialists, Omaha
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • CHI Health Good Samaritan, Kearney
  • Alegent Health Bergan Mercy Medical Center, Omaha
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer

  • University of Nebraska Medical Center, Omaha
RecruitingPhase 2
Ages 30 and older · Men · Updated Aug 19, 2026 · NCT07237269

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

  • CHI Health Saint Francis, Grand Island
  • CHI Health Good Samaritan, Kearney
  • Alegent Health Immanuel Medical Center, Omaha
  • and 2 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Integrated Cancer Repository for Cancer Research

  • Mary Lanning Healthcare, Morrison Cancer Center, Hastings
  • Faith Regional Health Services, Carson Cancer Center, Norfolk
  • Great Plains Regional Medical Center, North Platte
  • and 3 more
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

  • Nebraska Cancer Specialists (Midwest Cancer Center - Legacy), Omaha
  • XCancer Omaha / Urology Cancer Center, Omaha
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

  • Urology Cancer Center PC, Omaha
  • Nebraska Cancer Specialists, Omaha
RecruitingPhase 4
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

  • XCancer Omaha / Urology Cancer Center, Omaha
RecruitingPhase 1/2
Ages 18 and older · Men · Updated May 14, 2026 · NCT05413850

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

  • Research Site, Omaha
RecruitingPhase 1
Ages 18 and older · Men · Updated May 12, 2026 · NCT06879041

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

  • CHI Health Good Samaritan, Kearney
  • Saint Elizabeth Regional Medical Center, Lincoln
  • Alegent Health Immanuel Medical Center, Omaha
  • and 4 more
RecruitingPhase 2
Ages 18 and older · Men · Updated Jan 29, 2026 · NCT05806515

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

  • Nebraska Medicine-Bellevue, Bellevue
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
RecruitingPhase 3
Ages 18 and older · Men · Updated Jan 22, 2026 · NCT06470243

High-dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer

  • University of Nebraska Medical Center, Omaha
Recruiting
Ages 19 and older · Men · Updated Nov 5, 2025 · NCT05754580

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Omaha
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

  • Nebraska Medicine-Bellevue, Bellevue
  • Nebraska Methodist Hospital, Omaha
  • Nebraska Medicine-Village Pointe, Omaha
  • and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.