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Prostate Cancer clinical trials in South Carolina

43 studies for Prostate Cancer are looking for participants at sites in South Carolina.

Cities in South Carolina

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Medical University of South Carolina, Charleston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingObservational study
Ages 40 to 75 · Men · Updated Sep 28, 2026 · NCT07543757

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

  • Research Site, Myrtle Beach
RecruitingPhase 1/2
Ages 18 to 130 · Men · Updated Sep 25, 2026 · NCT07181161

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • Ralph H. Johnson VA Health Care System (RHJVAHCS)-Urology ( Site 0083), Charleston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Study in Patients With Metastatic Castration-Resistant Prostate Cancer

  • START Carolinas, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07719361

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

  • Grand Strand Medical Center, Myrtle Beach
  • Carolina Urologic Research Center, LLC, Myrtle Beach
  • Parkway Surgery Center, Myrtle Beach
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • South Texas Accelerated Research Therapeutics - Carolinas, Myrtle Beach
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

  • MUSC Hollings Cancer Center, Charleston
  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Myrtle Beach
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT05011383

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

  • START Carolinas, Myrtle Beach
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07332000

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

  • Lowcountry Urology Clinics, North Charleston
Recruiting
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • McLeod Regional Medical Center, Florence
  • Gibbs Cancer Center-Gaffney, Gaffney
  • Self Regional Healthcare, Greenwood
  • and 3 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

  • Medical University of South Carolina - Hollings Cancer Center, Charleston
  • Prisma Health Cancer Institute, Greenville
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07545811

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Saint Francis Hospital, Greenville
  • Saint Francis Cancer Center, Greenville
  • Self Regional Healthcare, Greenwood
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT06931340

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • AnMed Health Cancer Center, Anderson
  • Prisma Health Richland Hospital, Columbia
  • McLeod Regional Medical Center, Florence
  • and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • Gibbs Cancer Center-Gaffney, Gaffney
  • Gibbs Cancer Center-Pelham, Greer
  • Spartanburg Medical Center, Spartanburg
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06632977

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

  • Research Site, Myrtle Beach
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 26, 2026 · NCT07611110

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • Medical University of South Carolina, Charleston
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

  • Medical University of South Carolina, Charleston
RecruitingPhase 1
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs

  • Research Site, Myrtle Beach
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Aug 10, 2026 · NCT07336446

Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 31, 2026 · NCT06613100

PSMA PET Combined With MRI for the Detection of PCa

  • Atlantic Urology Specialists, Myrtle Beach
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · Men · Updated Jul 23, 2026 · NCT07052214

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

  • Medical University of South Carolina, Charleston
  • Levine Cancer Institute-Rock Hill, Rock Hill
RecruitingPhase 3
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

  • Carolina Urologic Research Center, the START Center for Cancer Research, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

  • South Texas Accelerated Research Therapeutics - Carolinas, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 2, 2026 · NCT07140900

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

  • Ralph H. Johnson VA Medical Center, Charleston
RecruitingObservational study
Ages 21 and older · Men · Updated May 22, 2026 · NCT03151629

T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer

  • Hollings Cancer Center at Medical University of South Carolina, Charleston
RecruitingPhase 2
Ages 18 and older · Men · Updated Mar 4, 2026 · NCT05586360

Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer

  • Medical University of South Carolina Hollings Cancer Center, Charleston
RecruitingPhase 2
Ages 18 and older · Men · Updated Feb 5, 2026 · NCT07325721

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

  • Carolina Urologic Research Center, Myrtle Beach
RecruitingPhase 1
Ages 18 and older · Men · Updated Feb 4, 2026 · NCT04729114

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

  • Medical University of South Carolina, Charleston
  • McLeod Health, Florence
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Vitamin D for Prostate Endocrine Therapy

  • Gibbs Cancer Center-Gaffney, Gaffney
  • Saint Francis Hospital, Greenville
  • Saint Francis Cancer Center, Greenville
  • and 3 more
RecruitingPhase 3
Ages 50 and older · Men · Updated Jan 15, 2026 · NCT05838716

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 123, Charleston
  • Research Site 108, Greenville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.