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Rectal Cancer clinical trials in California

22 studies for Rectal Cancer are looking for participants at sites in California.

Cities in California

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

  • Orange Coast Memorial Medical Center ( Site 2007), Fountain Valley
  • Los Angeles Hematology Oncology Medical Group ( Site 0084), Los Angeles
  • UCLA Hematology/Oncology - Santa Monica ( Site 0088), Santa Monica
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • UC IRVINE Health, Orange
  • UC Davis Comprehensive Cancer Center, Sacramento
  • Stanford Cancer Institute, Stanford
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • University of California, San Diego, La Jolla
  • Hoag Memorial Hospital Presbyterian, Newport Beach
  • Redwood City, Redwood City
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
  • Mercy Cancer Center - Carmichael, Carmichael
  • Mercy San Juan Medical Center, Carmichael
  • and 8 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • Kaiser Permanente-Anaheim, Anaheim
  • Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
  • PCR Oncology, Arroyo Grande
  • and 28 more
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Family Communications After Genetic Testing

  • Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank
  • Marshall Cancer Center, Cameron Park
  • and 17 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Distance-Based Exercise to Preserve Function and Prevent Disability

  • Kaiser Permanente Dublin, Dublin
  • Kaiser Permanente-Fremont, Fremont
  • Kaiser Permanente Fresno Orchard Plaza, Fresno
  • and 6 more
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07059884

Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

  • City of Hope Medical Center, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06834126

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
  • Los Angeles General Medical Center, Los Angeles
  • USC / Norris Comprehensive Cancer Center, Los Angeles
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

Early Onset Colorectal Cancer Detection

  • City of Hope Medical Center, Duarte
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Jul 7, 2026 · NCT06342401

Efficacy and Safety of the CG-100 Intraluminal Bypass Device

  • Kaiser Permanente San Diego medical Center, San Diego
Recruiting
Ages 22 to 70 · All sexes · Updated Jul 6, 2026 · NCT04184973

Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3

  • City of Hope Corona, Corona
  • City of Hope Medical Center, Duarte
  • City of Hope Seacliff, Huntington Beach
  • and 4 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07595874

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

  • City of Hope Medical Center, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT06780787

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

  • Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

  • UCSD Moores Cancer Center, La Jolla
  • UCLA Medical Center, Los Angeles
  • Stanford University, Stanford
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

  • Beckman Research Institute of City of Hope, Duarte
  • VA Medical Center, Fresno, Fresno
  • Santa Clara Valley Medical Center, Fruitdale
  • and 5 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT04703101

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

  • Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 99 · All sexes · Updated Feb 20, 2026 · NCT04907643

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Duarte
  • Massive Bio SYNERGY-AI site, Irvine
  • Massive Bio SYNERGY-AI site, La Jolla
  • and 3 more
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

  • UCSD Moores Cancer Center, La Jolla
  • UCLA Medical Center, Los Angeles
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems

  • University of California Los Angeles (UCLA), Los Angeles
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 6, 2021 · NCT03961776

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.