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Rectal Cancer clinical trials in Massachusetts

15 studies for Rectal Cancer are looking for participants at sites in Massachusetts.

Cities in Massachusetts

Distance-Based Exercise to Preserve Function and Prevent Disability

  • Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial

  • Dana-Farber Cancer Institute, Boston
  • Brigham and Women's Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06565052

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

  • Massachusetts General Hospital - Main Campus, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Resilience and Equity in Aging, Cancer, and Health (REACH)

  • Dana-Farber Cancer Institute, Boston
Recruiting
Ages 65 and older · All sexes · Updated Sep 10, 2026 · NCT04674267

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • Massachusetts General Hospital Cancer Center, Boston
  • Boston Veteran's Affairs Medical Center, Jamaica Plain
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07351071

RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer

  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07735624

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

  • Beverly Hospital, Beverly
  • Lahey Clinic, Burlington
  • Addison Gilbert Hospital, Gloucester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

  • Mass General Brigham Cancer Institute at Massachusetts General Hospital, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

Integrated Cancer Repository for Cancer Research

  • Holyoke Medical Center, Holyoke
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Massachusetts General Hospital, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

  • Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 11, 2026 · NCT03516708

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Worcester
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · All sexes · Updated May 18, 2025 · NCT05914766

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.