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Rectal Cancer clinical trials in Ohio

18 studies for Rectal Cancer are looking for participants at sites in Ohio.

Cities in Ohio

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

  • Miami Valley Hospital South ( Site 0075), Centerville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

  • GSK Investigational Site, Canton
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

  • University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06263088

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Cleveland Clinic, Cleveland
  • Toledo Clinic Cancer Center, Toledo
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • Bethesda North Hospital, Cincinnati
  • TriHealth Cancer Institute-Westside, Cincinnati
  • and 1 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

  • UHHS-Chagrin Highlands Medical Center, Beachwood
  • Miami Valley Hospital South, Centerville
  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • and 13 more
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Family Communications After Genetic Testing

  • Aultman Alliance Community Hospital, Alliance
  • Indu and Raj Soin Medical Center, Beavercreek
  • Saint Elizabeth Boardman Hospital, Boardman
  • and 17 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

  • The Ohio State University Wexner Medical Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07351071

ColoSealâ„¢ ICD System Anastomotic Protection Pivotal Study

  • Ohio State Medical University Center, Columbus
Recruiting
Ages 22 to 75 · All sexes · Updated Aug 21, 2026 · NCT07429110

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

  • Miami Valley Hospital South, Centerville
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • Ohio State University Comprehensive Cancer Center, Columbus
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

Integrated Cancer Repository for Cancer Research

  • Aultman Alliance Community Hospital, Alliance
  • Aultman Hospital, Canton
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

  • The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients

  • Ohio State University Comprehensive Cancer Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Apr 21, 2026 · NCT06424522

Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 2
Ages 50 and older · Women · Updated Apr 21, 2026 · NCT07407647

Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06746012

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

  • University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT04624555

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Cincinnati
  • Massive Bio SYNERGY-AI site, Columbus
  • Massive Bio SYNERGY-AI site, Mayfield Heights
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

  • The Ohio State University, Columbus
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.