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Rectal Cancer clinical trials in Pennsylvania
15 studies for Rectal Cancer are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
- St. Luke's University Health Network ( Site 2014), Easton
- UPMC Hillman Cancer Center ( Site 2024), Pittsburgh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- Allegheny Health Network, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors
- Lehigh Valley Health Network (Data Collection Only), Allentown
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04165772ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
- University of Pennsylvania, Philadelphia
- WellSpan Medical Oncology & Hematology at York Cancer Center, York
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- Christiana Care Health System-Concord Health Center, Chadds Ford
- and 8 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939Family Communications After Genetic Testing
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- Pocono Medical Center, East Stroudsburg
- and 2 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
- Saint Luke's Cancer Center - Allentown, Allentown
- Saint Luke's University Hospital-Bethlehem Campus, Bethlehem
- Geisinger Medical Center, Danville
- and 10 more
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
- Lankenau Institute for Medical Research, Wynnewood
Recruiting
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07351071Distance-Based Exercise to Preserve Function and Prevent Disability
- UPMC Hillman Cancer Center at Butler Health System, Butler
- IRMC Cancer Center, Indiana
- UPMC Hillman Cancer Center - New Castle, New Castle
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07059884Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer
- Christiana Care Health System-Concord Health Center, Chadds Ford
- Penn State Milton S Hershey Medical Center, Hershey
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation
- Sidney Kimmel Cancer Center, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
- Alliance Cancer Specialists, Wynnewood
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
- Allegheny Health Network, Pittsburgh
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305Adaptive Radiation Boost for Rectal Cancer
- Fox Chase Cancer Center, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Dec 9, 2025 · NCT07221058SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Philadelphia
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.