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Schizophrenia clinical trials in California

44 studies for Schizophrenia are looking for participants at sites in California.

Cities in California

Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia

  • Local Institution - 0190, Anaheim
  • Local Institution - 0040, Bellflower
  • Local Institution - 0188, Chino
  • and 10 more
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 28, 2026 · NCT07686263

A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia

  • CNS Network, Garden Grove
RecruitingPhase 1
Ages 18 to 55 · All sexes · Updated Sep 28, 2026 · NCT07615426

Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia

  • Neurocrine Clinical Site, Garden Grove
  • Neurocrine Clinical Site, La Habra
  • Neurocrine Clinical Site, Lemon Grove
  • and 2 more
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07227818

NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

  • Neurocrine Clinical Site, Cerritos
  • Neurocrine Clinical Site, Chino
  • Neurocrine Clinical Site, Culver City
  • and 9 more
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07114874

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

  • Advanced Research Center, Inc, Anaheim
  • National Institute Of Clinical Research, Garden Grove
  • Excell Research Inc, Oceanside
  • and 3 more
RecruitingPhase 3
Ages 5 to 17 · All sexes · Updated Sep 25, 2026 · NCT06229210

NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

  • Neurocrine Clinical Site, Culver City
  • Neurocrine Clinical Site, Garden Grove
  • Neurocrine Clinical Site, Riverside
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07105098

A Study of Brenipatide in Adult Participants With Schizophrenia

  • Clinical Innovations, Inc. dba CITrials, Bellflower
  • Collaborative Neuroscience Research, LLC, Garden Grove
  • Catalina Research Institute, LLC, Montclair
  • and 3 more
RecruitingPhase 2
Ages 18 to 55 · All sexes · Updated Sep 22, 2026 · NCT07410507

A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

  • Advanced Research Center Inc., Anaheim
  • Local Institution - 0159, Anaheim
  • Inland Psychiatric Medical Group., Chino
  • and 7 more
RecruitingPhase 3
Ages 5 to 17 · All sexes · Updated Sep 22, 2026 · NCT07424404

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

  • Neurocrine Clinical Site, Chino
  • Neurocrine Clinical Site, Fresno
  • Neurocrine Clinical Site, Long Beach
  • and 3 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07105111

A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia

  • Collaborative Neuroscience Research, LLC, Los Alamitos
RecruitingPhase 1
Ages 18 to 55 · All sexes · Updated Sep 17, 2026 · NCT07734493

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

  • California Clinical Trials Medical Group - Parexel /ID# 275751, Glendale
  • CenExel Collaborative Neuroscience Research /ID# 273005, Los Alamitos
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 15, 2026 · NCT07145918

52-week Open Label Safety-Tolerability Study

  • Advanced Research Center, Anaheim
  • Synapse Clinical Trials, Cerritos
  • ProScience Research Group, Culver City
  • and 2 more
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Sep 9, 2026 · NCT07369154

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

  • Advanced Research Center Inc., Anaheim
  • Inland Psychiatric Medical Group., Chino
  • Proscience Research Group, Culver City
  • and 1 more
RecruitingPhase 3
Ages 13 to 17 · All sexes · Updated Sep 4, 2026 · NCT07288567

A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

  • Collaborative Neuroscience Research, LLC, Los Alamitos
RecruitingPhase 1
Ages 18 to 55 · All sexes · Updated Sep 2, 2026 · NCT07061288

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

  • Clinical Site, Bellflower
  • Clinical Site, Cerritos
  • Clinical Site, Culver City
  • and 12 more
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT07459647

Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU)

  • ATP Clinical Research, Costa Mesa
  • Lumos Clinical Research Center, San Jose
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07101094

Enhancing Veteran-Clinical Collaboration in VA PRRCs

  • VA San Diego Healthcare System, San Diego, CA, San Diego
  • VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06898879

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

  • Pamoja Advanced Nursing Practice, Anaheim
  • Local Institution - 0003, Anaheim
  • Inland Psychiatric Medical Group (IPMG)-Chino, Chino
  • and 3 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07379827

Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder

  • Alkermes Investigator Site, Stanford
RecruitingPhase 3
Ages 10 to 17 · All sexes · Updated Aug 14, 2026 · NCT05303064

Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder

  • BioXcel Clinical Research Site, Anaheim
RecruitingPhase 1
Ages 10 to 17 · All sexes · Updated Aug 11, 2026 · NCT05025605

Inter-Brain Synchrony in Schizophrenia

  • University of California, Los Angeles, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Aug 11, 2026 · NCT07177261

Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode

  • UCLA Aftercare Research Program, Los Angeles
Recruiting
Ages 18 to 45 · All sexes · Updated Aug 4, 2026 · NCT05890183

Biomarkers to Enhance Early Schizophrenia Treatment

  • University of California San Diego, La Jolla
RecruitingPhase 4
Ages 18 to 35 · All sexes · Updated Jul 31, 2026 · NCT06969755

Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

  • CNRI Los Angeles LLC, Pico Rivera
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Jul 29, 2026 · NCT07467993

Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia

  • ProScience Research Group, Culver City
  • CenExel, Garden Grove
  • Synergy San Diego, Lemon Grove
  • and 1 more
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Jul 27, 2026 · NCT07363577

Tolerability of MDMA in Schizophrenia

  • UCLA, Los Angeles
RecruitingPhase 1/2
Ages 18 to 60 · All sexes · Updated Jul 17, 2026 · NCT05770375

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

  • Acacia Clinics, Sunnyvale
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Jul 16, 2026 · NCT06376734

A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

  • Synapse Clinical Trials, Cerritos
  • Synergy Research Center, Lemon Grove
  • Cenexel CNS, Los Alamitos
RecruitingPhase 2
Ages 18 to 55 · All sexes · Updated Jun 23, 2026 · NCT07191483

A Study to Evaluate the Effect of KarXT on Urological Safety

  • Clinical Innovations, Inc. dba CITrials, Bellflower
  • CenExel CNS - Garden Grove, Garden Grove
  • ATP Clinical Research, Orange
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Jun 3, 2026 · NCT07221877

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

  • University of California, Los Angeles, Los Angeles
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated May 4, 2026 · NCT05208190

Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia

  • UCLA Semel Institute, Los Angeles
RecruitingPhase 2
Ages 18 to 60 · All sexes · Updated Apr 28, 2026 · NCT05778591

Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia

  • Imaging Research Center, Sacramento
RecruitingHealthy volunteers welcome
Ages 18 to 47 · All sexes · Updated Mar 30, 2026 · NCT04267003

NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia

  • Neurocrine Clinical Site, Anaheim
  • Neurocrine Clinical Site, Pico Rivera
  • Neurocrine Clinical Site, San Diego
  • and 2 more
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Mar 6, 2026 · NCT06963034

Brain Stimulation to the Hippocampus in Schizophrenia

  • Stanford University, Stanford
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Feb 27, 2026 · NCT07010614

Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness (R33)

  • University of California - San Diego, San Diego
Recruiting
Ages 18 to 65 · All sexes · Updated Feb 23, 2026 · NCT06865937

Enhancing Rehabilitation for Veterans With Serious Mental Illness

  • VA San Diego Healthcare System, San Diego, CA, San Diego
Recruiting
Ages 18 to 83 · All sexes · Updated Jan 30, 2026 · NCT06586164

Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy

  • UC San Diego, San Diego
Recruiting
Ages 18 to 65 · All sexes · Updated Jan 23, 2026 · NCT07098169

Single and Multiple Ascending Doses of NTX-253 in Healthy Participants and Participants With Stable Schizophrenia

  • Collaborative Neuroscience Research, LLC - CenExel, Los Alamitos
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Jan 15, 2026 · NCT07344948

Randomized Withdrawal Study in Patients With Schizophrenia

  • Vanda Investigational Site, Costa Mesa
  • Vanda Investigational Site, Lemon Grove
  • Vanda Investigational Site, Oceanside
  • and 3 more
RecruitingPhase 3
Ages 18 to 65 · All sexes · Updated Jan 12, 2026 · NCT06961968

Study of ALTO-101 in Patients With Schizophrenia

  • Site 5038, Garden Grove
  • Site 5063, Los Angeles
  • Site 5106, Orange
  • and 1 more
RecruitingPhase 2
Ages 21 to 55 · All sexes · Updated Dec 26, 2025 · NCT06502964

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.