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Sickle Cell Disease clinical trials in Texas

11 studies for Sickle Cell Disease are looking for participants at sites in Texas.

Cities in Texas

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

  • Texas Childrens Cancer and Hematology Center, Houston
  • U of TX Health Science Ct, Houston
RecruitingPhase 3
Ages 12 to 100 · All sexes · Updated Sep 28, 2026 · NCT06439082

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

  • Texas Children's Hospital_Houston, Houston
  • UT Health University of Texas, Houston
RecruitingPhase 3
Ages 2 and older · All sexes · Updated Sep 18, 2026 · NCT06609226

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

  • UT Health University of Texas, Houston
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

  • UT Health Science Center, Houston
RecruitingPhase 1/2Healthy volunteers welcome
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

  • Children's Blood and Cancer Center of Central Texas, Austin
  • North Texas Hemophilia and Thrombosis Program - Pediatric Program / Center for Cancer & Blood Disorders, Dallas
  • North Texas Comprehensive Hemophilia Treatment Center, Dallas
  • and 3 more
RecruitingObservational study
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

  • Baylor College of Medicine- Site Number : 8400055, Houston
RecruitingPhase 3
Ages 10 to 65 · All sexes · Updated Jul 29, 2026 · NCT06975865

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

  • Texas Children's Hopsital (NT-DMT), Houston
  • Texas Children's Hospital (MRD-HCT), Houston
  • UT San Antonio (NT-DMT), San Antonio
RecruitingObservational study
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease

  • Site # 8400004, Houston
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Apr 15, 2026 · NCT07247188

Sickle Cell Kidney Biorepository

  • Parkland Memorial Hospital, Dallas
  • University of Texas Southwestern Medical Center, Dallas
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Apr 13, 2026 · NCT07064174

Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial

  • Baylor College of Medicine, Houston
RecruitingPhase 2
Ages 15 to 40 · All sexes · Updated Mar 13, 2026 · NCT06260891

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

  • University of Texas at Houston, Houston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 22, 2025 · NCT06385886

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.