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Steatotic Liver Disease clinical trials in California

22 studies for Steatotic Liver Disease are looking for participants at sites in California.

Cities in California

A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD

  • Southern California Research Center, Coronado
  • California Liver Research Institute, Pasadena
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07527910

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

  • University of California San Diego NAFLD Research Center, La Jolla
  • Keck Medical Center of USC, Los Angeles
  • LAC + USC Medical Center, Los Angeles
  • and 2 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT05832229

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

  • Southern California Research Center, Coronado
  • Om Research Llc, Lancaster
  • Clinnova Research Solutions, Orange
  • and 3 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT05519475

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

  • San Fernando Valley Health Institute, Canoga Park
  • Ark Clinical Research - Fountain Valley, Fountain Valley
  • Fresno Clinical Research Center, Fresno
  • and 11 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07165028

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

  • Akero Clinical Study Site, Coronado
  • Akero Clinical Study Site, Escondido
  • Akero Clinical Study Site, Folsom
  • and 13 more
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT06528314

A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH

  • GSK Investigational Site, Arcadia
  • GSK Investigational Site, Covina
  • GSK Investigational Site, Los Angeles
  • and 3 more
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 17, 2026 · NCT07221188

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

  • Om Research, Apple Valley
  • ARK Clinical Research - Fountain Valley, Fountain Valley
  • UCSD Medical Center, La Jolla
  • and 4 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 9, 2026 · NCT07288138

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

  • 89bio Clinical Study Site, Camarillo
  • 89bio Clinical Study Site, Canoga Park
  • 89bio Clinical Study Site, Coronado
  • and 10 more
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 3, 2026 · NCT06419374

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

  • 89bio Clinical Study Site, Canoga Park
  • 89bio Clinical Study Site, Coronado
  • 89bio Clinical Study Site, Escondido
  • and 13 more
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 3, 2026 · NCT06318169

A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

  • GSK Investigational Site, Coronado
  • GSK Investigational Site, Lancaster
  • GSK Investigational Site, Los Angeles
  • and 3 more
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Aug 3, 2026 · NCT06613698

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

  • GSK Investigational Site, Arcadia
  • GSK Investigational Site, Covina
  • GSK Investigational Site, Folsom
  • and 6 more
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Jul 27, 2026 · NCT07221227

A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

  • GSK Investigational Site, Fresno
  • GSK Investigational Site, Lancaster
  • GSK Investigational Site, Pasadena
  • and 2 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Jul 8, 2026 · NCT06920043

A Study of Efimosfermin Alfa in Adults With Hepatic Impairment

  • GSK Investigational Site, Rialto
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Jun 9, 2026 · NCT07358546

Bicalutamide Therapy in Young Women With NAFLD and PCOS

  • University of California San Francisco, San Francisco
RecruitingPhase 1
Ages 18 to 42 · Women · Updated May 29, 2026 · NCT05979389

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

  • Velocity Clinical research, Los Angeles
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Apr 16, 2026 · NCT05648214

Androgens and NAFLD Longitudinal Cohort Study

  • University of California San Francisco, San Francisco
RecruitingObservational study
Ages 18 to 42 · Women · Updated Apr 13, 2026 · NCT06124261

Accurate Point of Care Liver Disease Diagnostics (Phase 2)

  • University of California San Diego, La Jolla
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT07518784

Quantitative Ultrasound to Assess Steatotic Liver Disease in Children

  • University of California San Diego, La Jolla
RecruitingObservational study
Ages 9 to 18 · All sexes · Updated Jan 21, 2026 · NCT06706856

Implementing Food Referrals for Equity and Sustained Health

  • Rady Children's Hospital San Diego, San Diego
RecruitingPhase 2Healthy volunteers welcome
Ages 5 and older · All sexes · Updated Nov 19, 2025 · NCT06661538

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

  • Stanford University, Stanford
RecruitingHealthy volunteers welcome
Ages 35 to 65 · All sexes · Updated Dec 4, 2024 · NCT05165706

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.