Risk and Resilience to Suicide Following Late-Life Spousal Bereavement
Recruiting
Risk and Resilience to Late-life Suicidal Ideation and Behavior After Spousal Bereavement: Targeting Social Connectedness to Strengthen Circadian Rhythmicity
Who can join
Ages 60 and older · All sexes
Full eligibility criteria
Older adults who recently lost their spouse or life partner and are high risk for suicidal thoughts and/or behavior. Inclusion Criteria: 1. Bereaved \< or = to 12 months from spousal/partner loss (+ 4 weeks) 2. \> or = to 60 years old 3. Current major depressive episode (w/o psychotic features) as established by the MINI diagnostic interview. A) Subsyndromal or syndromal depression (\> 9 HDRS) B) Current major depressive episode (w/o psychotic features) as established by the MINI diagnostic interview. C) History of depression severe enough to trigger treatment (e.g., antidepressant, counselling). D) Verified history of unipolar or bipolar major depressive disorder (MDD)\*, \*Please note, we will include those with a life-time history of Manic or Hypomanic episode as established by the MINI diagnostic interview), if they are currently in a depressive episode. Even if there is no indication of depression (see A-D above), we include those who have A) history of suicide attempt 4. or currently have significant suicidal ideation (Scale of Suicidal Ideation score \>4) 5. Does not reside in nursing home 6. Not a current shift worker 7. No major cognitive impairment: TICS score of \> or = to 27 Exclusion Criteria: 1. Bereaved \>12 months (+ 4 weeks) from spousal/partner bereavement 2. \< 60 years old 3. Patient is not spousal/partner bereaved (ex: parent, sibling, etc.) 4. Diagnosis of schizophrenia/schizoaffective disorders 5. Current and/or lifetime history of psychosis (or medications listed indicate diagnosis of these disorders) 6. Current Manic or Hypomanic Episode (note past history of Manic or Hypomanic episodes are not exclusion) 7. Major cognitive impairment: TICS score of \<27 8. Current shift worker 9. Resides in a nursing home 10. Unstable medical condition (e.g., unstable angina, end stage renal disease) 11. Resides outside of PA, WV or OH
About the study
The purpose of the RISE study is to examine how the 24-hour rhythm of sleep and social activity relate to mood and suicidal ideation among older adults that recently lost a spouse or life partner.
What is being tested
- WELL Behavioral Probe (behavioral)
Sponsor: University of Pittsburgh · Participants: 169 · Started: Nov 20, 2023
Contact the study team
- Emilee Croswell, BA · Phone: 4124408418
Official record on ClinicalTrials.gov — NCT06191484
Locations in the U.S.
| Pennsylvania | University of Pittsburgh (UPMC), Pittsburgh |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.