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Temporomandibular Disorders clinical trials recruiting in the U.S.
12 studies for Temporomandibular Disorders are recruiting participants at sites across the United States.
Temporomandibular disorders (TMDs) affect the joints that connect your lower jaw to your skull. TMDs can cause jaw pain and stiffness. Learn about treatments.
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Recently updated studies
Effects of Vagus Nerve Stimulation on Temporomandibular Disorders.
Recruiting
Ages 18 to 50 · Women · Updated Sep 1, 2026 · NCT07288411Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 74 · All sexes · Updated Aug 14, 2026 · NCT06617494JIT: Effect of Pain on DT in TMD
RecruitingEarly phase 1Healthy volunteers welcome
Ages 21 to 65 · All sexes · Updated Jul 9, 2026 · NCT06659991Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
Recruiting
Ages 18 to 88 · All sexes · Updated Jul 7, 2026 · NCT06214923Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain
Recruiting
Ages 18 to 80 · All sexes · Updated Jun 29, 2026 · NCT06977100K23- Physical Self Regulation vs Placebo
Recruiting
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06357702An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular Disorders
Recruiting
Ages 12 and older · All sexes · Updated Jun 10, 2026 · NCT07639944Evaluating Noninvasive Brain Stimulation for TMD Pain: A Feasibility Study
Recruiting
Ages 18 to 65 · All sexes · Updated May 29, 2026 · NCT07517172Postural Perturbations Tracing to the Stomatognathic System
Recruiting
Ages 30 to 65 · All sexes · Updated Dec 4, 2025 · NCT06974591Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
RecruitingHealthy volunteers welcome
All ages · All sexes · Updated Dec 2, 2025 · NCT05317390Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 19, 2025 · NCT05754190The Effect of Manual Physical Therapy and Exercise in Addition to Routine Dental Care in Individuals With Temporomandibular Disorders
Recruiting
Ages 18 to 55 · All sexes · Updated Feb 5, 2025 · NCT06602375From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.