Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)

Inclusion Criteria:

* Age (18-88 years)
* English speaker (written and spoken)
* Temporal Mandibular Disorder (TMD) for at least 3 months
* TMD Grade Chronic Pain Scale (GCPS) ≥ 0

Exclusion Criteria:

* Present or past degenerative neuromuscular disease
* Cardiovascular, neurological diseases, pulmonary abnormalities, kidney disease, liver disease, history of cancer within past 3 years
* Cervical pain (e.g. stenosis, radiculopathy)
* Any personal (or family first degree) history of mania, schizophrenia, or other psychoses
* Severe psychiatric condition (e.g. schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years.
* Use of Antipsychotics (e.g., Risperdal, Ability and clozaril)Lifetime alcohol/drug dependence or alcohol/drug abuse in past 3 months
* Pregnancy or breast feeding
* Color-blindness
* Impaired or uncorrected hearing
* Non-dominant hand
* Any facial trauma that has occurred in the last 6 weeks
* History of a severe facial trauma in the last 2-3 months
* Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection)
* Known history of severe motion sickness
* Non-removable head cover, artificial hair, certain types of braids or dreadlocks
* History of fainting
* History of angioedema
* Failed drug test (testing for opiates, cocaine, methamphetamines, and amphetamines)