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Ulcerative Colitis clinical trials in Massachusetts

18 studies for Ulcerative Colitis are looking for participants at sites in Massachusetts.

Cities in Massachusetts

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

  • Massachusetts General Hospital Cancer Center, Boston
  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Nov 4, 2026 · NCT06937086

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

  • Brigham and Women's Hospital, Boston
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT07186101

Safety, Dosage, and Microbiome Engraftment Study of MGT-006 for Ulcerative Colitis (ROOT Study)

  • Brigham and Women's Hospital, Boston
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Nov 3, 2026 · NCT07913347

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

  • Gastro Health Research - Framingham, Framingham
  • Lucida Clinical Trials LLC, New Bedford
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Oct 28, 2026 · NCT06581328

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

  • Lucida Clinical Trials /ID# 282000, New Bedford
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 27, 2026 · NCT07697456

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

  • Boston Children's Hospital, Boston
RecruitingPhase 2
Ages 12 to 17 · All sexes · Updated Oct 27, 2026 · NCT05287126

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

  • Site 003, Boston
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 27, 2026 · NCT07012395

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

  • Massachusetts General Hospital, Boston
Recruiting
Ages 18 to 85 · All sexes · Updated Oct 23, 2026 · NCT05987852

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

  • Tufts Medical Center - Site Number: 8400126, Boston
  • UMass Memorial Medical Center - Site Number: 8400121, Worcester
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Oct 23, 2026 · NCT07184996

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

  • Boston Children's Hospital, Boston
  • University of Massachusetts Chan Medical School, Worcester
RecruitingPhase 2/3
Ages 2 to 17 · All sexes · Updated Oct 20, 2026 · NCT05076175

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

  • UMass Memorial Medical Center-Site Number: 8400121, Worcester
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Oct 16, 2026 · NCT07185009

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

  • Boston Children's Hospital, Boston
  • Massachusetts General Hospital, Waltham
RecruitingPhase 3
Ages 2 to 19 · All sexes · Updated Oct 7, 2026 · NCT04844606

Family Members at INcreased-risk for Developing Inflammatory Bowel Disease

  • Massachusetts General Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 14 and older · All sexes · Updated Oct 7, 2026 · NCT06655415

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

  • Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

Treatment of UC With Novel Therapeutics

  • Brigham and Women's Hospital, Chestnut Hill
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Jul 21, 2026 · NCT06420375

Study of Novel Therapeutics for Acute Remedy of Colitis

  • Brigham and Women's Hospital, Chestnut Hill
  • Brigham and Women's Hospital, Chestnut Hill
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 20, 2025 · NCT06420492

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

  • Boston Children's Hospital, Boston
RecruitingObservational study
Ages 5 to 25 · All sexes · Updated Mar 3, 2025 · NCT04331639

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.