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Ulcerative Colitis clinical trials in Boston, MA

12 studies for Ulcerative Colitis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

RecruitingPhase 2
  • Site 003, Boston
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07012395

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

RecruitingPhase 2/3
  • Boston Children's Hospital, Boston
Ages 2 to 17 · All sexes · Updated Sep 24, 2026 · NCT05076175

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • Massachusetts General Hospital Cancer Center, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

RecruitingPhase 2
  • Brigham and Women's Hospital, Boston
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07186101

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

RecruitingPhase 3
  • Boston Children's Hospital, Boston
Ages 2 to 19 · All sexes · Updated Sep 22, 2026 · NCT04844606

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 3
  • Tufts Medical Center - Site Number: 8400126, Boston
Ages 16 to 80 · All sexes · Updated Aug 20, 2026 · NCT07184996

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

RecruitingObservational study
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

RecruitingPhase 2
  • Boston Children's Hospital, Boston
Ages 12 to 17 · All sexes · Updated Jul 8, 2026 · NCT05287126

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

RecruitingPhase 2
  • Investigational Site Number: 8400017, Boston
Ages 18 to 75 · All sexes · Updated Apr 23, 2026 · NCT06975722

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Jan 8, 2026 · NCT05987852

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

RecruitingObservational study
  • Boston Children's Hospital, Boston
Ages 5 to 25 · All sexes · Updated Mar 3, 2025 · NCT04331639

Family Members At INcreased-risk for Developing Inflammatory Bowel Disease

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 14 and older · All sexes · Updated Dec 20, 2024 · NCT06655415

About Ulcerative Colitis

Ulcerative Colitis (UC) can cause long-lasting swelling and ulcers in the large intestine. It is a type of inflammatory bowel disease. Find out more.

More about Ulcerative Colitis on MedlinePlus

Ulcerative Colitis trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.