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Ulcerative Colitis clinical trials in Boston, MA

12 studies for Ulcerative Colitis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • Massachusetts General Hospital Cancer Center, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

RecruitingPhase 2
  • Brigham and Women's Hospital, Boston
Ages 18 to 80 · All sexes · Updated Nov 4, 2026 · NCT07186101

Safety, Dosage, and Microbiome Engraftment Study of MGT-006 for Ulcerative Colitis (ROOT Study)

RecruitingPhase 1/2
  • Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Nov 3, 2026 · NCT07913347

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

RecruitingPhase 2
  • Boston Children's Hospital, Boston
Ages 12 to 17 · All sexes · Updated Oct 27, 2026 · NCT05287126

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

RecruitingPhase 2
  • Site 003, Boston
Ages 18 to 75 · All sexes · Updated Oct 27, 2026 · NCT07012395

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Oct 23, 2026 · NCT05987852

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 3
  • Tufts Medical Center - Site Number: 8400126, Boston
Ages 16 to 80 · All sexes · Updated Oct 23, 2026 · NCT07184996

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

RecruitingPhase 2/3
  • Boston Children's Hospital, Boston
Ages 2 to 17 · All sexes · Updated Oct 20, 2026 · NCT05076175

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

RecruitingPhase 3
  • Boston Children's Hospital, Boston
Ages 2 to 19 · All sexes · Updated Oct 7, 2026 · NCT04844606

Family Members at INcreased-risk for Developing Inflammatory Bowel Disease

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 14 and older · All sexes · Updated Oct 7, 2026 · NCT06655415

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

RecruitingObservational study
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

RecruitingObservational study
  • Boston Children's Hospital, Boston
Ages 5 to 25 · All sexes · Updated Mar 3, 2025 · NCT04331639

About Ulcerative Colitis

Ulcerative Colitis (UC) can cause long-lasting swelling and ulcers in the large intestine. It is a type of inflammatory bowel disease. Find out more.

More about Ulcerative Colitis on MedlinePlus

Ulcerative Colitis trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.