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Chronic Lymphocytic Leukemia clinical trials in Houston, TX

17 studies for Chronic Lymphocytic Leukemia are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

RecruitingPhase 1
  • Houston Methodist Hospital, Houston
  • Texas Children's Hospital, Houston
Up to age 75 · All sexes · Updated Oct 2, 2026 · NCT01853631

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • UT MD Anderson Cancer Center, Houston
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

RecruitingPhase 1/2
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06542250

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

RecruitingPhase 1/2
  • Md Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05006716

Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies

RecruitingPhase 3
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07648264

Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04169737

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

RecruitingPhase 1/2
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06564038

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

RecruitingPhase 1/2
  • MD Anderson, Houston
Ages 12 and older · All sexes · Updated Sep 3, 2026 · NCT04588922

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

RecruitingPhase 1/2
  • University of Texas MD Anderson Cancer Center, Houston
Ages 13 to 90 · All sexes · Updated Aug 6, 2026 · NCT06533579

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT04830137

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

RecruitingPhase 4
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876662

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

RecruitingPhase 4
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876649

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

RecruitingPhase 1
  • Oncology Consultants, Houston
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Dec 10, 2025 · NCT05602363

Chronic Lymphocytic Leukemia trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.