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Head and Neck Cancer clinical trials in Portland, OR

8 studies for Head and Neck Cancer are looking for participants at sites in and around Portland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Oregon Health & Science University (OHSU), Portland
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0113, Portland
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 6, Portland
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Providence Cancer Institute Franz Clinic, Portland
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy

Recruiting
  • Oregon Health and Science University, Portland
Ages 18 to 85 · All sexes · Updated Feb 12, 2026 · NCT07405645

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health Sciences University, Portland
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Portland
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Head and Neck Cancer

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes. Read the different symptoms of each type.

More about Head and Neck Cancer on MedlinePlus

Head and Neck Cancer trials in other cities

Other studies in Portland

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.