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Pulmonary Arterial Hypertension clinical trials recruiting in the U.S.

33 studies for Pulmonary Arterial Hypertension are recruiting participants at sites across the United States.

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Recently updated studies

A Study of Inhaled Treprostinil (LIQ861) in Adults With Pulmonary Arterial Hypertension Transitioning From Oral Selexipag

RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Oct 2, 2026 · NCT07759804

Spironolactone for Pulmonary Arterial Hypertension

RecruitingPhase 2
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT01712620

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07218029

Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07318597

Hormonal, Metabolic, and Signaling Interactions in PAH

RecruitingObservational studyHealthy volunteers welcome
Up to age 90 · All sexes · Updated Sep 25, 2026 · NCT01884051

A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07143448

An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Sep 2, 2026 · NCT07365332

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404

The MObile Health InterVEntion in Pulmonary Arterial Hypertension (MOVE PAH) Study

Recruiting
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05464095

Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06992440

Xenon MRI Pulm Hypertension

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 10, 2026 · NCT04991454

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Jul 29, 2026 · NCT06274801

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Jul 21, 2026 · NCT06649110

A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 45 · Women · Updated May 26, 2026 · NCT07312227

Repurposing Valsartan May Protect Against Pulmonary Hypertension

RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated May 4, 2026 · NCT06053580

A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial Hypertension

RecruitingPhase 1
Ages 18 to 60 · All sexes · Updated Apr 23, 2026 · NCT06872112

Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

RecruitingPhase 2
Ages 1 to 17 · All sexes · Updated Apr 20, 2026 · NCT05587712

Mobile Health Intervention to Improve Exercise in Pediatric PH

Recruiting
Ages 10 to 21 · All sexes · Updated Mar 27, 2026 · NCT06549452

Pulmonary Hypertension SOLAR

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 24, 2026 · NCT04778046

129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Feb 24, 2026 · NCT06104228

129 Xenon Imaging in Patients Treated With Sotatercept

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Feb 24, 2026 · NCT06351345

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.