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Cancer (all types) clinical trials in North Carolina
90 studies for Cancer (all types) are looking for participants at sites in North Carolina.
Cities in North Carolina
A Study of Mocertatug Rezetecan in Combination With Anti-cancer Therapies for Advanced Solid Tumors (BEHOLD-2)
- GSK Investigational Site, Durham
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06796907Distance-Based Exercise to Preserve Function and Prevent Disability
- Novant Health Cancer Institute - Kernersville, Kernersville
- Novant Health Cancer Institute - Mount Airy, Mount Airy
- Novant Health Forsyth Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
- The University of North Carolina Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05874921Registry Study for Radiation Therapy Outcomes
- Atrium Health Levine Cancer Proton & Advanced Radiation Center, Charlotte
RecruitingObservational study
All ages · All sexes · Updated Sep 29, 2026 · NCT01255748A Study of PHN-012 in Patients With Advanced Solid Tumors
- PHN-012-001 Site, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
- Messino Cancer Centers Asheville, Asheville
- Duke University Medical Center, Durham
- FirstHealth Cancer Center, Pinehurst
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
- East Carolina University, Greenville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07195591A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
- UNC Hospitals, The University of North Carolina at Chapel Hill, Chapel Hill
- Levine Cancer Institute, Charlotte
- University of North Carolina Hospitals at Hillsborough, Hillsborough
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
- Levine Cancer Institute, Charlotte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06150157A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
- University of North Carolina at Chapel Hill, Chapel Hill
- Duke University Medical Center - Duke Cancer Centre, Durham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06901531Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
- Quetzal Site 27, Chapel Hill
RecruitingPhase 3
Ages 18 to 71 · All sexes · Updated Sep 23, 2026 · NCT07504458A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
- FirstHealth of the Carolinas- Speciality Center /ID# 279857, Pinehurst
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241Study of the Effect of Innate on the Inflammatory Response to Endotoxin
- NIEHS Clinical Research Unit (CRU), Research Triangle Park
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 100 · All sexes · Updated Sep 22, 2026 · NCT01143480TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
- Lineberger Comprehensive Cancer Center, Chapel Hill
- Atrium Health's Levine Cancer Institute, Charlotte
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535Prospective Study to Assess a Diagnostic Aid for Cancer
- Wilmington Health, PLLC, Wilmington
RecruitingObservational study
Ages 45 and older · All sexes · Updated Sep 21, 2026 · NCT07046260Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
- The University of North Carolina at Chapel Hill, Chapel Hill
- Levine Cancer Institute, Charlotte
- Duke University Medical Center, Durham
- and 1 more
RecruitingPhase 2/3
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796Digital Art Therapy for Young Cancer Survivors
- Lineberger Comprehensive Cancer Center, Chapel Hill
Recruiting
Ages 18 to 25 · All sexes · Updated Sep 17, 2026 · NCT06789666Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
- Lineberger Comprehensive Cancer Center at University of North Carolina Chapel Hill, Chapel Hill
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06096038RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
- University of North Carolina at Chapel Hill /ID# 272454, Chapel Hill
- Atrium Health Levine Cancer Institute /ID# 271510, Charlotte
- Wake Forest Baptist Health /ID# 271294, Winston-Salem
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06953960A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
- Research Site, Charlotte
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482A Phase 1/1b Study of IAM1363 in HER2 Cancers
- Duke Cancer Institute, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
- University of North Carolina Medical Center, Chapel Hill
- Duke Cancer Institute, Durham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
- Oncology Specialists of Charlotte, Charlotte
- Southern Oncology Specialists, Huntersville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07169851Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
- Duke Cancer Center, Durham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06252649Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
- Regional Medical Oncology Center_Wlson, Wilson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612Comprehensive Care for AYA: Needs Assessment Survey
- Atrium Health Levine Cancer, Charlotte
- Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingObservational study
Ages 15 and older · All sexes · Updated Aug 27, 2026 · NCT07196241A Study of ARC-02 in B-cell NHL
- Levine Cancer Institute, Charlotte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07691606Project: Every Child for Younger Patients With Cancer
- Mission Hospital, Asheville
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill
- Carolinas Medical Center/Levine Cancer Institute, Charlotte
- and 4 more
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
- University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 18 to 39 · All sexes · Updated Aug 24, 2026 · NCT06848491Abatacept in Immune Checkpoint Inhibitor Myocarditis
- University of North Carolina Chapel Hill, Chapel Hill
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
- Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingPhase 1
Ages 18 to 99 · All sexes · Updated Aug 19, 2026 · NCT03454035FOG-001 in Locally Advanced or Metastatic Solid Tumors
- Duke University, Durham
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264Behavioral Pain Intervention for Older Cancer Patients
- Duke Cancer Network, Durham
Recruiting
Ages 55 and older · Women · Updated Aug 12, 2026 · NCT07300995A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
- Duke Cancer Institute, Durham
RecruitingPhase 1
Ages 18 and older · Men · Updated Aug 10, 2026 · NCT06067841Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Aug 10, 2026 · NCT07061652Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
- UNC Lineberger Comprehensive Cancer Center, Chapel Hill
- Duke University Medical Center, Durham
- Duke Women's Cancer Care Raleigh, Raleigh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer
- Atrium Health Levine Cancer, Charlotte
- Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingObservational study
Ages 50 and older · Women · Updated Jul 30, 2026 · NCT07046936Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
- FirstHealth of the Carolinas, Inc., Pinehurst
RecruitingPhase 3
Ages 18 and older · Women · Updated Jul 28, 2026 · NCT07022483Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors
- Levine Childrens Hospital Pediatric Cancer and Blood Disorders, Charlotte
- Levine Cancer Institute, Charlotte
- Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06634381From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.