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Colorectal Cancer clinical trials in Kentucky

19 studies for Colorectal Cancer are looking for participants at sites in Kentucky.

Cities in Kentucky

Family Communications After Genetic Testing

  • CommonSpirit Saint Joseph Hospital - Bardstown, Bardstown
  • Commonwealth Cancer Center-Corbin, Corbin
  • CommonSpirit Saint Joseph Hospital - Lexington, Lexington
  • and 4 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

  • Baptist Health Louisville, Louisville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • CommonSpirit Saint Joseph Hospital - Bardstown, Bardstown
  • Commonwealth Cancer Center-Corbin, Corbin
  • Saint Elizabeth Healthcare Edgewood, Edgewood
  • and 5 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Baptist Health Hardin, Elizabethtown
  • Frankfort BHMG Medical Oncology Office, Frankfort
  • Baptist Health Lexington, Lexington
  • and 9 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

  • Norton Cancer Institute - MDC, Louisville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06004245

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

  • University of Kentucky/Markey Cancer Center, Lexington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

  • Clinical Study Site, Edgewood
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

  • Norton Cancer Institute - Downtown, Louisville
  • Norton Cancer Institute, Downtown, Louisville
  • Norton Hospital, Louisville
  • and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651

Lead-212 PSV359 Therapy for Patients With Solid Tumors

  • University of Kentucky, Lexington
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

  • Norton Cancer Institute - Norton Healthcare Pavilion, Louisville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT07169734

Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

  • University of Louisville Hospital, Louisville
Recruiting
Ages 21 and older · All sexes · Updated Jun 16, 2026 · NCT07337590

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

  • UK Markey Cancer Center, Lexington
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

  • University of Kentucky, Lexington
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT04779554

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

  • Flaget Memorial Hospital, Bardstown
  • Commonwealth Cancer Center-Corbin, Corbin
  • Saint Joseph Hospital, Lexington
  • and 4 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Flaget Memorial Hospital, Bardstown
  • Saint Joseph Hospital East, Lexington
  • Saint Joseph London, London
  • and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

  • Baptist Corbin, Corbin
  • Baptist Hardin, Elizabethtown
  • Baptist Lexington, Lexington
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

GENOCARE: A Prospective, Randomized Clinical Trial of Genotype-Guided Dosing Versus Usual Care

  • University of Kentucky, Lexington
Recruiting
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT05391126

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.