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Crohn's Disease clinical trials in Massachusetts
27 studies for Crohn's Disease are looking for participants at sites in Massachusetts.
Cities in Massachusetts
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
- Massachusetts General Hospital-Crohn's and Colitis Center ( Site 5037), Boston
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Oct 2, 2026 · NCT06430801Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
- Lucida Clinical Trials /ID# 282000, New Bedford
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 2, 2026 · NCT07697456Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance
- Massachusetts General Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Oct 2, 2026 · NCT07033208A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
- Gastro Health Research - Framingham, Framingham
- Lucida Clinical Trials LLC, New Bedford
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT06581328A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
- Boston Childrens Hospital, Boston
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Sep 25, 2026 · NCT05923073Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
- Lucida Clinical Trials /ID# 266548, New Bedford
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
- Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07499232Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
- Lucida Clinical Trials, New Bedford
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
- Massachusetts General Hospital Cancer Center, Boston
- Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
- Tufts Medical Center-Site Number: 8400126, Boston
- UMass Memorial Medical Center-Site Number: 8400121, Worcester
RecruitingPhase 3
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
- Massachusetts General Hospital - Mass General Waltham /ID# 255767, Waltham
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Sep 23, 2026 · NCT05995353A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
- Boston Children's Hospital, Boston
- Massachusetts General Hospital, Waltham
RecruitingPhase 3
Ages 2 to 19 · All sexes · Updated Sep 22, 2026 · NCT04844606A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
- Boston Children's Hospital, Boston
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Aug 24, 2026 · NCT05509777Zymfentra (Infliximab-dyyb) REal World Cohort STudy
- Brigham and Women's Hospital, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516Low Dose IL-2 for the Treatment of Crohn's Disease
- Boston Children's Hospital, Boston
- Brigham and Women's Hospital, Boston
RecruitingPhase 1/2
Ages 12 to 80 · All sexes · Updated Aug 3, 2026 · NCT04263831Cranberry and Gut Health in Crohn's Disease
- UMASS medical center, Worcester
RecruitingEarly phase 1
Ages 18 to 65 · All sexes · Updated Jul 20, 2026 · NCT07170462Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
- Boston Children's Hospital /ID# 262191, Boston
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated Jun 24, 2026 · NCT06332534Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease
- Boston Children's Hospital, Boston
RecruitingPhase 4
Ages 6 to 17 · All sexes · Updated May 27, 2026 · NCT05781152A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
- Boston Children's Hospital, Boston
RecruitingPhase 3
Ages 2 to 17 · All sexes · Updated May 5, 2026 · NCT04779320Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
- Lucida Clinical Trials, LLC, New Bedford
- University of Massachusetts, Worcester, Worcester
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Apr 27, 2026 · NCT06456593A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease
- Investigational Site Number: 8400022, Boston
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Mar 27, 2026 · NCT06958536Value of PET/MR Enterography in the Assessment of Crohn's Disease Using a Collagen-binding Radiotracer.
- Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Mar 12, 2026 · NCT06252493Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility
- Massachusetts General Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 14 and older · All sexes · Updated Jan 30, 2026 · NCT05332639A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule
- Massachusetts General Hospital, Boston
RecruitingHealthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Dec 16, 2025 · NCT07219537Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease
- Boston Children's Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 13 to 20 · All sexes · Updated Oct 30, 2025 · NCT04508088High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy
- Boston Children's Hospital, Boston
RecruitingObservational study
Ages 5 to 25 · All sexes · Updated Mar 3, 2025 · NCT04331639Family Members At INcreased-risk for Developing Inflammatory Bowel Disease
- Massachusetts General Hospital, Boston
RecruitingObservational studyHealthy volunteers welcome
Ages 14 and older · All sexes · Updated Dec 20, 2024 · NCT06655415From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.