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Heart Diseases clinical trials in California

21 studies for Heart Diseases are looking for participants at sites in California.

Cities in California

Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions

  • San Diego State University, San Diego
RecruitingHealthy volunteers welcome
Ages 6 and older · All sexes · Updated Oct 2, 2026 · NCT06596902

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

  • UCSF Medical Center at Parnassus, San Francisco
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07087184

ELEVATE-HFpEF Clinical Study

  • Stanford University, Palo Alto
  • Sutter Health Hospital, San Francisco
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

  • University of California, San Diego, San Diego
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT07137338

Transition to KPL-387 Monotherapy Dosing & Administration Study

  • Investigational Site 014, Los Angeles
  • Investigational Site 002, Santa Monica
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT07288216

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

  • Scripps Memorial Hospital, La Jolla
  • PIH Health Good Samaritan Hospital, Los Angeles
  • Kaiser Permanente Los Angeles Medical Center, Los Angeles
  • and 6 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

  • Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Clinical Course Of Disease In Participants With FA-CM

  • University of California San Diego, La Jolla
RecruitingObservational study
Ages 6 and older · All sexes · Updated Sep 2, 2026 · NCT06865482

Abbott Structural Heart Device Registry

  • USC University Hospital, Los Angeles
RecruitingObservational study
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

  • Cedars-Sinai Medical Center, Los Angeles
  • UC Davis Health, Sacramento
  • Los Robles Regional Medical Center, Thousand Oaks
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07130994

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  • University of California, San Diego (UCSD) - Medical Center, La Jolla
  • University of California, Los Angeles (UCLA) - David Geffen School of Medicine, Los Angeles
  • University of California, San Francisco (UCSF), San Francisco
  • and 1 more
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

  • USC, Los Angeles
  • UCSF Medical Center, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

  • Sutter Medical Center, Sacramento
  • University of California at San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

  • Keck School of Medicine of USC, Los Angeles
  • UCLA Medical Center, Los Angeles
  • Stanford University, Redwood City
  • and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

  • Cedars-Sinai Medical Center, Los Angeles
  • Pomona Valley Hospital Medical Center, Pomona
  • University of California, San Francisco, San Francisco
Recruiting
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

Lumason® Infusion vs. Bolus Administrations

  • Interventional Cardiology Medical Group, West Hills
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06400004

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

  • Abcentra Investigational Site, Los Angeles
  • Abcentra Investigational Site, Torrance
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jan 27, 2026 · NCT06927739

PARTNER 3 Trial - Aortic Valve-in-Valve

  • University of California Los Angeles, Los Angeles
  • Sutter Medical Center, Sacramento
  • Stanford University Medical Center, Stanford
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299

MyGeneRank: A Digital Platform for Next-Generation Genetic Studies

  • Scripps Translational Science Institute, La Jolla
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 17, 2024 · NCT03277365

Heart Disease of the Small Arteries in Women and Men

  • Cedars-Sinai Women's Heart Center, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Sep 1, 2023 · NCT00573027

Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

  • Southern California Hospital at Culver City / Southern California Hospital at Hollywood / Multiple US-based Sub-Investigator Sites, Culver City
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 29, 2022 · NCT04684602

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.