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Non-Small Cell Lung Cancer clinical trials in Harrisburg, PA

12 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Harrisburg (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

RecruitingPhase 2
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07293247

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #104, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • Penn State Milton S. Hershey Medical Center, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

RecruitingPhase 3
  • Penn State Milton S. Hershey Medical Center-Penn State Cancer Institute ( Site 0059), Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312137

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • Research Site, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06692738

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

RecruitingPhase 3
  • Research Site, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07291037

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 3
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
  • Penn State Milton S Hershey Medical Center, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06686771

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus, Harrisburg
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion, Mechanicsburg · 8 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

RecruitingPhase 2
  • Penn State Cancer Institute, Hershey · 12 mi away
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT04317534

Non-Small Cell Lung Cancer trials in other cities

Other studies in Harrisburg

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.