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Non-Small Cell Lung Cancer clinical trials in Richmond, VA

25 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Richmond (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Virginia Cancer Institute, Richmond
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

RecruitingPhase 3
  • VCU Health Adult Outpatient Pavillion ( Site 0193), Richmond
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06623422

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Virginia Cancer Institute, Richmond
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • VCU Medical Center Gateway Building, Richmond
  • Virginia Commonwealth University, Richmond
  • VCU Health Short Pump Pavilion, Richmond
  • and 4 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07144280

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

RecruitingPhase 1/2
  • VCU Medical Center Gateway Building, Richmond
  • Virginia Commonwealth University, Richmond
  • VCU Health Stony Point, Richmond
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07227298

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

RecruitingPhase 3
  • VCU Health Adult Outpatient Pavillion, Richmond
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06890598

Pan-tumor MRD Study

RecruitingObservational study
  • Virginia Cancer Institute, Richmond
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

RecruitingPhase 3
  • Research Site, Richmond
  • Research Site, Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06357533

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • VCU Massey Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

RecruitingPhase 2/3
  • Virginia Commonwealth University (Vcu), Richmond
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07100080

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Richmond
  • Clinical Study Site, Richmond
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Virginia Cancer Institute - West End, Richmond
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • VCU Health Adult Outpatient Pavillion, Richmond
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

RecruitingPhase 3
  • Research Site, Midlothian · 11 mi away
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06350097

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 3
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06686771

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • VCU Medical Center (Virginia Commonwealth University), Richmond
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • Virginia Commonwealth University, Richmond
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06731413

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Virginia Cancer Institute, Richmond
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Virginia Cancer Institute, Richmond
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

RecruitingPhase 2
  • Virginia Commonwealth University, Richmond
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT04317534

Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases

RecruitingPhase 2
  • Virginia Commonwealth University, Richmond
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT06248606

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • VCU Massey Cancer Center at Stony Point, Richmond
  • Virginia Commonwealth University/Massey Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Repositioning Immunotherapy in VetArans With Lung Cancer

RecruitingPhase 2
  • Richmond VA Medical Center, Richmond, VA, Richmond
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06275360

Non-Small Cell Lung Cancer trials in other cities

Other studies in Richmond

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.