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Pancreatic Cancer clinical trials in Ohio
45 studies for Pancreatic Cancer are looking for participants at sites in Ohio.
Cities in Ohio
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
- University Hospitals Cleveland Medical Center, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
- Taylor Cancer Research Center, Maumee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene
- Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
- Cleveland Clinic - Oncology Department, Cleveland
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06760819DESTINY-PANTUMOUR04
- Research Site, Canton
- Research Site, Maumee
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
- The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
- Taylor Cancer Research Center, Maumee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
- Facilities Design and Construction - Energy Advancement and Innovation Center, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07409272Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain
- University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07117032Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
- University of Cincinnati Medical Center, Cincinnati
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
- Investigative Site US050, Cleveland
- Investigative Site US020, Cleveland
- Investigative Site US033, Columbus
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073A Study Evaluating a New Radiation Treatment Workflow (NGDS)
- University Hospital Cleveland Medical Center, Cleveland
Recruiting
Ages 21 and older · All sexes · Updated Sep 17, 2026 · NCT07824583EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.
- University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06263088Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?
- Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT05720338Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
- Cincinnati Children's Hospital Medical Center, Cincinnati
- Nationwide Children's Hospital, Columbus
RecruitingObservational study
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach
- UH Cleveland Medical Center, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT05764720A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
- The Ohio State University (OSU) Wexner Medical Center, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers
- Ohio State University Comprehensive Cancer Center, Columbus
RecruitingObservational study
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573The Vanguard Study: Testing a New Way to Screen for Cancer
- Louis Stokes Cleveland VA Medical Center, Cleveland
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
- Aultman Health Foundation, Canton
- Miami Valley Hospital South, Centerville
- University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
- and 11 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328Pancreatic Cancer Early Detection Consortium
- The Ohio State University, Columbus
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056Integrated Cancer Repository for Cancer Research
- Aultman Alliance Community Hospital, Alliance
- Aultman Hospital, Canton
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699Ultra-High Resolution Optical Coherence Tomography in Detecting Micrometer Sized Early Stage Pancreatic Cancer in Participants With Pancreatic Cancer
- Ohio State University Comprehensive Cancer Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03711890A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
- The Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
- Ohio State University-James Cancer Hospital and Solove Research Institute, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT04890613Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
- The Christ Hospital, Cincinnati
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
- Miami Valley Hospital South, Centerville
- University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
- Good Samaritan Hospital - Cincinnati, Cincinnati
- and 10 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06998940Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
- Christ Hospital Cancer Center, Cincinnati
- Taylor Cancer Research Center, Maumee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study
- Ohio State University Comprehensive Cancer Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT05961982Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response
- The Ohio State University, Columbus
Recruiting
Ages 19 and older · All sexes · Updated Feb 27, 2026 · NCT04588025A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer
- Taylor Cancer Center, Maumee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT07049055A Brief Psychological Intervention to Improve Emotional Well-Being During Neoadjuvant Therapy for Pancreatic Cancer
- Ohio State University Comprehensive Cancer Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT07124611Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
- Cleveland Clinic, Cleveland
- Taylor Cancer Research Center, Maumee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations
- Ohio State University-Telemedicine, Cincinnati
- Ohio State University-Telemedicine, Cleveland
- Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- Cleveland Clinic, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
- Cleveland Clinic Foundation, Cleveland
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT06973564LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
- Strecker Cancer Center-Belpre, Belpre
- Marietta Memorial Hospital, Marietta
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
- Taylor Cancer Research Center (site 204), Maumee
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Cincinnati
- Massive Bio SYNERGY-AI site, Columbus
- Massive Bio SYNERGY-AI site, Mayfield Heights
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774The Cancer of the Pancreas Screening-5 CAPS5)Study
- Case Comprehensive Cancer Center, Case Western Medical Reserve, Cleveland
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT02000089From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.