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Head and Neck Squamous Cell Carcinoma clinical trials in Richmond, VA

12 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Richmond (within about 30 miles). Open a study to see who can join and how to contact the study team.

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0129, Richmond
  • Site #0138, Richmond
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

RecruitingPhase 3
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06589804

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

RecruitingPhase 2
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06980038

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Virginia Cancer Institute, Richmond
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Virginia Commonwealth University Massey Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

RecruitingPhase 2
  • VCU Massey Cancer Center at Stony Point, Richmond
  • VCU Massey Comprehensive Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

Enhancing Oral Cancer Awareness

RecruitingHealthy volunteers welcome
  • Virginia Commonwealth University, Richmond
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06682494

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • VCU Massey Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06064877

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Bon Secours, Richmond
  • Virginia Commonwealth University, Richmond
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05962242

Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

RecruitingPhase 2
  • Massey Cancer Center, Richmond
Ages 18 and older · All sexes · Updated Mar 18, 2024 · NCT05280314

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Richmond

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.