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Prostate Cancer clinical trials in Colorado

40 studies for Prostate Cancer are looking for participants at sites in Colorado.

Cities in Colorado

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • Rocky Mountain Cancer Center, Denver
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

  • Rocky Mountain Regional VA Medical Center, Aurora
  • Kaiser Permanente-Franklin, Denver
  • Shaw Cancer Center, Edwards
  • and 3 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

  • UCHealth University of Colorado Hospital, Aurora
  • UCHealth Memorial Hospital Central, Colorado Springs
  • Memorial Hospital North, Colorado Springs
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT07200830

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • Sarah Cannon Research Institute at HealthOne, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Rocky Mountain Regional VA Medical Center, Aurora
  • UCHealth University of Colorado Hospital, Aurora
  • Penrose-Saint Francis Healthcare, Colorado Springs
  • and 15 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • UCHealth Memorial Hospital Central, Colorado Springs
  • Memorial Hospital North, Colorado Springs
  • Poudre Valley Hospital, Fort Collins
  • and 3 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

  • University of Colorado Anschutz Medical Campus, Aurora
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06095089

DESTINY-PANTUMOUR04

  • Research Site, Boulder
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

  • Rocky Mountain Cancer Center, Colorado Springs
  • Sarah Cannon Research Institute 1, Denver
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

  • University of Colorado Anschutz Medical Campus ( Site 0046), Aurora
  • UCHealth Highlands Ranch Hospital ( Site 0111), Highlands Ranch
  • Colorado Clinical Research ( Site 0067), Lakewood
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

  • Rocky Mountain Cancer Centers, Denver
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

  • Rocky Mountain Cancer Centers, Denver
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

  • Research Site, Lakewood
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

  • GSK Investigational Site, Denver
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06990880

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

  • Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT05011383

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

  • Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

  • Rocky Mountain Regional Veterans Affairs Medical Center ( Site 0053), Aurora
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

  • Colorado Clinical Research, Lakewood
  • Urology Associates, Littleton
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07332000

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

  • Rocky Mountain Cancer Centers, Denver
  • United States Oncology Regulatory Affairs Corporate Office, Denver
  • US Oncology Research Investigational Products Center, Denver
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07493512

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

  • UCHealth University of Colorado Hospital, Aurora
  • Rocky Mountain Cancer Centers-Penrose, Colorado Springs
  • UCHealth Memorial Hospital Central, Colorado Springs
  • and 2 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

The Vanguard Study: Testing a New Way to Screen for Cancer

  • Keefe Memorial Hospital, Cheyenne Wells
  • Kaiser Permanente-Franklin, Denver
  • Poudre Valley Hospital, Fort Collins
  • and 5 more
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

  • Sarah Cannon Research Institute - Denver DDU, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

  • Research Site, Aurora
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 26, 2026 · NCT07611110

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

  • Rocky Mountain Cancer Center, Colorado Springs
RecruitingPhase 2
Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

  • Rocky Mountain Cancer Centers, Aurora
RecruitingPhase 1
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT04221542

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

  • University of Colorado Health, Aurora
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

  • Penrose-Saint Francis Healthcare, Colorado Springs
  • Rocky Mountain Cancer Centers-Penrose, Colorado Springs
  • Saint Francis Cancer Center, Colorado Springs
  • and 6 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • University of Colorado, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

  • UCHealth University of Colorado Hospital, Aurora
  • Penrose-Saint Francis Healthcare, Colorado Springs
  • Rocky Mountain Cancer Centers-Penrose, Colorado Springs
  • and 18 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

  • Rocky Mountain Cancer Center, Colorado Springs
RecruitingPhase 1
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Integrated Cancer Repository for Cancer Research

  • Advent Health, Greenwood Village
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

  • University of Colorado, Aurora
RecruitingPhase 4
Ages 18 to 100 · Men · Updated Jun 4, 2026 · NCT05803941

Pragmatic Trial of Metformin for Glucose Intolerance or Increased BMI in Prostate Cancer Patients

  • Colorado Research Center, Aurora
  • UCHealth-Southern Colorado, Colorado Springs
  • UCHealth-Metro Denver, Denver
  • and 1 more
RecruitingEarly phase 1
Ages 18 and older · Men · Updated Jun 2, 2026 · NCT05515978

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

  • Sarah Cannon Research Institute, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors

  • University of Colorado Anschutz Medical Campus, Aurora
RecruitingPhase 2
Ages 18 to 89 · All sexes · Updated Feb 5, 2026 · NCT07001241

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

  • Penrose-Saint Francis Healthcare, Colorado Springs
  • Rocky Mountain Cancer Centers-Penrose, Colorado Springs
  • Saint Francis Cancer Center, Colorado Springs
  • and 8 more
RecruitingPhase 2
Ages 18 and older · Men · Updated Jan 29, 2026 · NCT05806515

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Aurora
  • Massive Bio SYNERGY-AI site, Denver
  • Massive Bio SYNERGY-AI site, Littleton
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

  • University of Colorado Hospital, Aurora
  • Rocky Mountain Cancer Centers-Boulder, Boulder
  • UCHealth Memorial Hospital Central, Colorado Springs
  • and 8 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.