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Amyotrophic Lateral Sclerosis clinical trials in Pennsylvania

19 studies for Amyotrophic Lateral Sclerosis are looking for participants at sites in Pennsylvania.

Cities in Pennsylvania

Developing New Ways to Detect Respiratory Impairment Early in ALS

  • Thomas Jefferson University - Center City, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07844590

Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

  • Neuroscience Department at LKSM at Temple University, Philadelphia
RecruitingPhase 3
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07322003

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

  • University of Pennsylvania, Philadelphia
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

  • University of Pennsylvania, Philadelphia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07287397

Biofluid Research on Age-Related or Inherited Neurodegeneration

  • University of Pennsylvania, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07798700

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

  • Zydus US009, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07023835

ASSESS ALL ALS Study

  • Penn State Health, Hershey
  • University of Pennsylvania, Philadelphia
  • Temple University, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

PREVENT ALL ALS Study

  • Penn State Health, Hershey
  • Temple University, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

  • Speech Core, Pennsylvania State University, University Park
RecruitingHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Aug 7, 2026 · NCT06266403

Study of COYA 302 for the Treatment of ALS

  • Thomas Jefferson University-Weinberg ALS Center, Philadelphia
  • Temple Neurology, Philadelphia
RecruitingPhase 2/3
Ages 18 to 80 · All sexes · Updated Aug 6, 2026 · NCT07161999

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  • University of Pennsylvania, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

  • Penn State Hershey ALS Clinic, Hershey
  • Penn Comprehensive ALS Center at Pennsylvania Hospital, Philadelphia
  • Thomas Jefferson University Weinberg ALS Center, Philadelphi
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT07071935

ALS/MND Natural History Study Data Repository

  • Thomas Jefferson University, Philadelphia
  • Temple University Lewis Katz School of Medicine, Philadelphia
  • University of Pittsburgh, Pittsburgh
RecruitingObservational study
Ages 18 to 90 · All sexes · Updated May 20, 2026 · NCT05966038

INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility Study

  • University of Pittsburgh Medical Center (UPMC), Pittsburgh
Recruiting
Ages 22 and older · All sexes · Updated May 11, 2026 · NCT07543367

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

  • Temple University of the Commonwealth System of Higher Education, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT06665165

Examining Interactions Between PALS and Caregivers

  • Speech Core, Pennsylvania State University, University Park
RecruitingHealthy volunteers welcome
Ages 18 to 90 · All sexes · Updated Apr 6, 2026 · NCT06819124

Assessing Perceptual Effects of Interactive Tasks

  • Speech Core, Pennsylvania State University, University Park
RecruitingHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Feb 12, 2026 · NCT06828523

UPenn Observational Research Repository on Neurodegenerative Disease

  • University of Pennsylvania, Philadelphia
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 22, 2026 · NCT04715399

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.