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Breast Cancer clinical trials in Phoenix, AZ

25 studies for Breast Cancer are looking for participants at sites in and around Phoenix (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Cancer Center at Saint Joseph's, Phoenix
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

RecruitingPhase 2
  • Mayo Clinic Hospital, Phoenix
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06369285

PRE-ISPY Phase I/II Oncology Platform Program

RecruitingPhase 1/2
  • Mayo Clinic Comprehensive Cancer Center, Phoenix
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05868226

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • Mayo Clinic Cancer Center ( Site 0034), Phoenix
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

RecruitingPhase 3
  • Ironwood Cancer & Research Centers, Phoenix
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT06377852

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

RecruitingPhase 2
  • Mayo Clinic Building-Phoenix, Phoenix
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Recruiting
  • Mayo Clinic Arizona, Phoenix
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07214532

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Mayo Clinic in Arizona - Phoenix, Phoenix
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

RecruitingPhase 2
  • Mayo Clinic in Arizona - Phoenix, Phoenix
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07287098

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Banner University Medical Center - Phoenix Campus (Banner Good Samaritan Medical Center), Phoenix
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

Breast Cancer, Reasoning, and Activity Intervention

Recruiting
  • Mayo Clinic in Arizona, Phoenix
Ages 50 and older · Women · Updated Sep 8, 2026 · NCT04816006

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

RecruitingPhase 3
  • Mayo Clinic-Comprehensive Cancer Center-Breast Clinic, Phoenix
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • Mayo Clinic Hospital in Arizona, Phoenix
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • USOR HonorHealth, Phoenix
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Mayo Clinic Hospital in Arizona, Phoenix
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • Mayo Clinic Comprehensive Cancer Center, Phoenix
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

Recruiting
  • Arizona State University, Phoenix
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT06938555

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Cancer Center at Saint Joseph's, Phoenix
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Mayo Clinic, Phoenix
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Cancer Center at Saint Joseph's, Phoenix
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Clinical Validation of Early Detection Blood Test for Universal Large-scale Breast Cancer Screening

RecruitingObservational studyHealthy volunteers welcome
  • Vincere Cancer Center, Phoenix
Ages 30 to 75 · Women · Updated Mar 11, 2026 · NCT07219277

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

RecruitingObservational study
  • Arizona Oncology Associates, PC, Phoenix
Ages 18 and older · All sexes · Updated Aug 20, 2025 · NCT03053193

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Phoenix

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.