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Lung Cancer clinical trials in San Francisco, CA

23 studies for Lung Cancer are looking for participants at sites in and around San Francisco (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • California Pacific Medical Center-Pacific Campus, San Francisco
  • Kaiser Permanente-San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

Smoking Cessation CM for Veterans With or at Risk for Cancer

RecruitingHealthy volunteers welcome
  • San Francisco VA Medical Center, San Francisco, CA, San Francisco
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06432985

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • Kaiser Permanente-San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Kaiser Permanente-San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT04181060

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Kaiser Permanente-San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • University of California, San Francisco (UCSF), San Francisco
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

RecruitingPhase 1
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • California Pacific Medical Center-Pacific Campus, San Francisco
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

RecruitingPhase 2
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06518057

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • UCSF Medical Center - Mission Bay, San Francisco
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

CONNECTing to LungCare

RecruitingHealthy volunteers welcome
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT06213532

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • California Pacific Medical Center-Pacific Campus, San Francisco
  • Kaiser Permanente-San Francisco, San Francisco
  • Veterans Affairs Medical Center - San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • UCSF Comprehensive Cancer Center, San Francisco
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT07164313

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • California Pacific Medical Center-Pacific Campus, San Francisco
  • Kaiser Permanente-San Francisco, San Francisco
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Kaiser Permanente-San Francisco, San Francisco
  • Veterans Affairs Medical Center - San Francisco, San Francisco
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Recruiting
  • Zuckerberg San Francisco General, San Francisco
  • Kaiser Foundation Research Institute, San Francisco
  • University of San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • University of California at San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • University of California San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center, San Francisco
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, San Francisco
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in San Francisco

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.