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Prostate Cancer clinical trials in San Francisco, CA

45 studies for Prostate Cancer are looking for participants at sites in and around San Francisco (within about 30 miles). Open a study to see who can join and how to contact the study team.

Precision-Based Genomics in Prostate Cancer

RecruitingObservational study

University of California San Francisco, San Francisco

Ages 18 to 120 · Men · Updated Sep 28, 2026 · NCT04706663

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3

San Francisco VA Health Care System ( Site 0093), San Francisco

Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Recruiting

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3

Kaiser Permanente-San Francisco, San Francisco

Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

RecruitingPhase 2

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05766371

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3

Kaiser Permanente-San Francisco, San Francisco

Ages 18 and older · Men · Updated Sep 2, 2026 · NCT06931340

Prostate Active Surveillance Study

RecruitingObservational study

Veterans Affairs San Francisco Health Care System, San Francisco
University of California, San Francisco, San Francisco

Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665

A Study of Tarlatamab for People With Prostate Cancer

RecruitingPhase 2

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Aug 31, 2026 · NCT07111507

Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617

RecruitingPhase 1

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Aug 28, 2026 · NCT07054346

COMPASS Study for Metastatic Castration-resistant Prostate Cancer

RecruitingObservational study

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

Ages 18 and older · Men · Updated Aug 27, 2026 · NCT07050433

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

RecruitingPhase 3

Research Site, San Francisco

Ages 18 and older · Men · Updated Aug 26, 2026 · NCT07611110

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Aug 21, 2026 · NCT04221542

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

RecruitingPhase 2

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2

University of California San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco

Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2

Research Site, San Francisco

Ages 18 to 130 · All sexes · Updated Aug 12, 2026 · NCT05417594

A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs

RecruitingPhase 1/2

Research Site, San Francisco

Ages 18 and older · Men · Updated Aug 10, 2026 · NCT07336446

A Study of DM002 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2

University of California San Francisco Cancer Center, San Francisco

Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06751329

Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

RecruitingPhase 1

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Jul 31, 2026 · NCT06613100

Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

RecruitingPhase 1/2

University of California, San Francisco, San Francisco

Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT05113537

Imaging of Solid Tumors Using 18F-TRX

RecruitingPhase 1

University of California, San Francisco, San Francisco

Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06942104

PSMA PET Combined With MRI for the Detection of PCa

RecruitingPhase 3Healthy volunteers welcome

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Jul 23, 2026 · NCT07052214

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

RecruitingPhase 1

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

Social, Structural, and Lifestyle Drivers of Prostate Cancer Disparities

RecruitingObservational study

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Jul 8, 2026 · NCT07690579

Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

RecruitingPhase 2

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Jul 7, 2026 · NCT06526299

Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

RecruitingPhase 1

University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Jul 2, 2026 · NCT07140900

Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

RecruitingPhase 2

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Jun 4, 2026 · NCT03821246

177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

RecruitingPhase 1

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Jun 1, 2026 · NCT07145177

Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance

RecruitingPhase 2

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated May 18, 2026 · NCT03933670

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

RecruitingObservational studyHealthy volunteers welcome

University of California, San Francisco, San Francisco

Ages 40 and older · Men · Updated May 15, 2026 · NCT04472338

Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr

Recruiting

UCSF, San Francisco

Ages 18 and older · Men · Updated May 4, 2026 · NCT05948657

Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer

RecruitingEarly phase 1

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Apr 30, 2026 · NCT02526368

Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate Cancer

Recruiting

University of California, San Francisco

Ages 18 and older · Men · Updated Apr 16, 2026 · NCT06171139

Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

RecruitingPhase 3

Kaiser Permanente-San Francisco, San Francisco

Ages 18 and older · Men · Updated Apr 14, 2026 · NCT06235697

Mechanisms of Resistance to PSMA Radioligand Therapy

RecruitingObservational study

University of California, San Francisco, San Francisco

Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT05435495

64Cu-GRIP B in Patients With Advanced Malignancies

RecruitingPhase 1/2

University of California, San Francisco, San Francisco

Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT05888532

Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer

Recruiting

San Francisco Veterans Affairs Medical Center, San Francisco

Ages 18 and older · All sexes · Updated Mar 9, 2026 · NCT05396872

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

RecruitingPhase 1/2

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07145255

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1

University of California San Francisco, San Francisco

Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

Magnetic Resonance (MR) Imaging With Hyperpolarized 13C-Pyruvate +/- 13C,15N-Urea in Patients With Prostate Cancer

RecruitingPhase 2

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Jan 7, 2026 · NCT06391034

Community-Based Health Coach for Access to Germline Genetic Testing Among African American Men With Prostate Cancer

Recruiting

Zuckerberg San Francisco General Hospital, San Francisco
San Francisco Veterans Administration Medical Center, San Francisco
University of California San Francisco, San Francisco

Ages 18 and older · Men · Updated Dec 31, 2025 · NCT04763980

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study

Massive Bio SYNERGY-AI site, San Francisco

All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3

Kaiser Permanente-San Francisco, San Francisco

Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer

RecruitingObservational study

University of California, San Francisco, San Francisco

Ages 18 and older · Men · Updated Nov 6, 2024 · NCT06579417

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in San Francisco

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.