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Melanoma clinical trials in San Francisco, CA

22 studies for Melanoma are looking for participants at sites in and around San Francisco (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)

RecruitingPhase 2
  • UCSF Medical Center at Mission Bay ( Site 4044), San Francisco
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06961006

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • University of California San Francisco (UCSF), San Francisco
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

Intratumoral N17350 in Advanced Solid Tumors

RecruitingPhase 1/2
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0096, San Francisco
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

RecruitingPhase 1/2
  • University of California-San Fransisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07287917

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

RecruitingPhase 1
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • UCSF Medical Center-Mission Bay, San Francisco
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • UCSF Medical Center-Mission Bay, San Francisco
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

RecruitingPhase 2
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT04598009

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

RecruitingPhase 1/2
  • UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06425926

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • UCSF Wayne and Gladys Valley Center for Vision, San Francisco
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Recruiting
  • Zuckerberg San Francisco General, San Francisco
  • Kaiser Foundation Research Institute, San Francisco
  • University of San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

RecruitingPhase 1/2
  • University of California San Francisco (UCSF), San Francisco
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06413680

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

RecruitingPhase 2/3
  • UCSF, San Francisco
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT06624644

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

RecruitingPhase 1
  • UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06326411

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Kaiser Permanente-San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

ACTengine® IMA203 Combined With mRNA-4203

RecruitingPhase 1
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Jan 8, 2026 · NCT06946225

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

RecruitingPhase 2
  • California Pacific Medical Center - Sutter Health, San Francisco
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT07237100

Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma

RecruitingObservational study
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT07148245

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, San Francisco
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of IBI363 in Subjects with Advanced Solid Malignancies

RecruitingPhase 2
  • University of California, San Francisco (UCSF), San Francisco
Ages 18 and older · All sexes · Updated Dec 19, 2024 · NCT06281678

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in San Francisco

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.