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Metastatic Cancer clinical trials in Charlotte, NC

11 studies for Metastatic Cancer are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
  • Levine Children's Hospital- Pediatric Neuro-Oncology, Charlotte
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

RecruitingPhase 2/3
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

RecruitingPhase 1/2
  • Atrium Health Levine Cancer Institute, Charlotte
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Levine Cancer Institute, Charlotte
  • Oncology Specialists of Charlotte, Charlotte
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • Carolina Biooncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

RecruitingPhase 1/2
  • Carolina Biooncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04977453

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

RecruitingPhase 1/2
  • Levine Cancer Institute, Charlotte
Ages 18 and older · Women · Updated Sep 3, 2026 · NCT04802759

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

RecruitingPhase 1/2
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT05431270

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

RecruitingPhase 1/2
  • Levine Cancer Institute (LCI)- Atrium Health, Charlotte
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT05735080

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Metastatic Cancer trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.