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Breast Cancer clinical trials in Miami, FL
42 studies for Breast Cancer are looking for participants at sites in and around Miami (within about 30 miles). Open a study to see who can join and how to contact the study team.
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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
RecruitingPhase 3
- Dwoskin Proton Therapy Center, Miami
- Miami Cancer Institute, Miami
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
RecruitingPhase 3
- Miami Cancer Institute, Miami
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
RecruitingPhase 3
- Research Site, Miami
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
- Sylvester Comprehensive Cancer Center, Miami
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Recruiting
- Werheim Cancer Institute, Miami
Precise Oncology Interventions in Nutrition and Training (OnPoint)
RecruitingHealthy volunteers welcome
- University of Miami, Miami
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami
Women Informed to Screen Depending on Measures of Risk (Wisdom Study)
RecruitingHealthy volunteers welcome
- TopLine MD Alliance, Miami
Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer
RecruitingPhase 2
- Baptist Alliance Miami Cancer Institute, Miami
A Study of Breast Cancer Risk Factors and Outcomes of People in Florida
RecruitingObservational studyHealthy volunteers welcome
- University of Miami (Data Collection Only), Miami
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
RecruitingPhase 3
- Miami Cancer Institute at Baptist Health Inc., Miami
- University of Miami, Miami
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
RecruitingPhase 1
- University of Miami, Miami
A Phase 1/1b Study of IAM1363 in HER2 Cancers
RecruitingPhase 1
- University of Miami, Miami
A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
RecruitingPhase 2
- BAPTIST ALLIANCE - MCI (Data Collection Only), Miami
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
RecruitingPhase 1/2
- Sylvester Comprehensive Cancer Center, Miami
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
- Miami Cancer Institute, Miami
- UM Sylvester Comprehensive Cancer Center at Kendall, Miami
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- University Of Miami-SCCC-Miami, Miami
- University of Miami_SCCC - Kendall, Miami
ATEMPT 2.0: Adjuvant T-DM1 vs TH
RecruitingPhase 2
- Miami Cancer Institute/Baptist Hospital of Miami, Miami
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
RecruitingPhase 3
- University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
- Miami Cancer Institute, Miami
- UM Sylvester Comprehensive Cancer Center at Kendall, Miami
Sequencing Antibody Drug Conjugates in ER+/HER2 LOW/ULTRA LOW MBC
RecruitingPhase 2
- Baptist Health Herbert Wertheim Cancer Institute, Miami
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
RecruitingPhase 3
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
RecruitingPhase 2
- Miami Baptist Cancer Institute/, Miami
SABER Study for Selected Early Stage Breast Cancer
Recruiting
- University of Miami, Miami
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
RecruitingPhase 2
- University of Miami Hospital and Clinics, Miami
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
RecruitingPhase 3
- Miami Cancer Institute, Miami
Phase III Trial of Brain MRI Surveillance in Stage IV Breast Cancer
RecruitingPhase 3
- Baptist Health South Florida, Miami
A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials
RecruitingObservational studyHealthy volunteers welcome
- University of Miami, Miami
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
- Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
RecruitingPhase 2
- Miami Cancer Institute at Baptist Health (Kendall), Miami
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer
RecruitingPhase 1/2
- Miami Cancer Institute at Baptist Health, Miami
Application of Chinese Herbal Complementary and Alternative Medicine (CAM) to Improve Human Health and to Further Botanical and Horticultural Sciences
Recruiting
- University of Miami, Miami
Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease
RecruitingPhase 2
- Baptist Alliance - McI, Miami
With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
Recruiting
- University of Miami, Miami
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
RecruitingPhase 1
- University of Miami - Sylvester Comprehensive Cancer Center, Miami
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
RecruitingObservational studyHealthy volunteers welcome
- Miami Cancer Institute, Miami
Breast Re-irradiation After Second Ipsilateral Lumpectomy
Recruiting
- Miami Cancer Institute at Baptist Health, Inc., Miami
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Miami
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
RecruitingObservational study
- Sylvester Comprehensive Cancer Center - University of Miami, Miami
- Miami Cancer Institute at Baptist Health, Inc, Miami
A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
RecruitingPhase 2
- AP Medical Research, Miami
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY134 studies
- Houston, TX126 studies
- Boston, MA111 studies
- Nashville, TN80 studies
- Los Angeles, CA72 studies
- Edison, NJ68 studies
- St. Louis, MO64 studies
- Durham, NC63 studies
- Queens, NY63 studies
- Chicago, IL58 studies
- Philadelphia, PA56 studies
- Dallas, TX55 studies
Other studies in Miami
- Cancer (all types)36 studies
- Non-Small Cell Lung Cancer31 studies
- Prostate Cancer27 studies
- Obesity27 studies
- Acute Myeloid Leukemia24 studies
- Metastatic Cancer24 studies
- Ovarian Cancer23 studies
- Overweight23 studies
- Multiple Myeloma21 studies
- Ulcerative Colitis21 studies
- Alzheimer's Disease20 studies
- Lung Cancer20 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.