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Breast Cancer clinical trials in Rochester, NY

15 studies for Breast Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

RecruitingPhase 2
  • University of Rochester Medical Center, Rochester
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06369285

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Recruiting
  • University of Rochester (URMC), Rochester
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07214532

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

RecruitingPhase 2
  • Wilmot Cancer Institute, Rochester
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07287098

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

RecruitingPhase 3
  • Rochester General Hospital Lipson Cancer Institute, Rochester
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • University of Rochester Medical, Rochester
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors

RecruitingPhase 1
  • Wilmot Cancer Institute, Rochester
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT05307705

Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

RecruitingPhase 2
  • University of Rochester Medical Center, Rochester
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT04886531

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • University of Rochester - Wilmot Cancer Institute, Rochester
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

RecruitingPhase 2
  • University of Rochester Wilmot Cancer Institute, Rochester
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Wilmot Cancer Institute Radiation Oncology at Greece, Rochester
  • Highland Hospital, Rochester
  • Pluta Cancer Center, Rochester
  • and 3 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers

Recruiting
  • University of Rochester, Rochester
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06896474

Access to Genetic Testing in Underserved Patients With Cancer

RecruitingHealthy volunteers welcome
  • University of Rochester, Rochester
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06422455

Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling

RecruitingPhase 2
  • University of Rochester, Rochester
Ages 18 and older · All sexes · Updated Dec 15, 2025 · NCT04965064

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

RecruitingObservational study
  • University of Rochester - Pluta Cancer Center, Rochester
Ages 18 and older · All sexes · Updated Aug 20, 2025 · NCT03053193

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

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Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.