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Depression clinical trials in Maryland
29 studies for Depression are looking for participants at sites in Maryland.
Cities in Maryland
Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 3 to 99 · All sexes · Updated Oct 2, 2026 · NCT00024635Long-term Observation of Participants With Mood Disorders
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Oct 1, 2026 · NCT04877977[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Oct 1, 2026 · NCT05703685Natural History of Depression, Bipolar Disorder and Suicide Risk
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 1, 2026 · NCT06462196A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
- Pharmasite Research, Inc., Baltimore
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Oct 1, 2026 · NCT07775300Characterization and Treatment of Adolescent Depression
- National Institutes of Health Clinical Center, Bethesda
RecruitingObservational studyHealthy volunteers welcome
Ages 11 to 25 · All sexes · Updated Sep 28, 2026 · NCT03388606A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
- Delricht Research - Rockville, Rockville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
- Sunstone Medical, PC, Rockville
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06793397Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT03065335RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Sunstone Therapies, PC, Rockville
- Sheppard Pratt, Towson
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 14, 2026 · NCT06511908Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT03973268Neurobiology of Suicide
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT02543983A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
- Pharmasite Research Inc., Baltimore
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407Psilocybin in Chronic Low Back Pain and Depression
- Johns Hopkins University School of Medicine, Baltimore
RecruitingPhase 1
Ages 21 to 80 · All sexes · Updated Sep 4, 2026 · NCT06355414Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
- Johns Hopkins Center for Psychedelic and Consciousness Research, Baltimore
RecruitingEarly phase 1
Ages 18 to 85 · All sexes · Updated Sep 4, 2026 · NCT04123314A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
- Draig Clinical Site, Gaithersburg
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Aug 26, 2026 · NCT07300969PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)
- National Institutes of Health Clinical Center, Bethesda
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Aug 18, 2026 · NCT04582916A Study of Brenipatide in Adult Participants With Major Depressive Disorder
- Pharmasite Research, Inc., Baltimore
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 6, 2026 · NCT07412756E-Mindfulness Approaches for Living After Breast Cancer
- Maryland Proton Treatment Center, Baltimore
- University of Maryland/Greenebaum Cancer Center, Baltimore
- MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore
- and 14 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, Gaithersburg
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401Strength and Pain-Coping Through Resilience and Knowledge
- Johns Hopkins School of Nursing, Baltimore
Recruiting
Ages 50 and older · All sexes · Updated Jul 22, 2026 · NCT07228520CAPABLE Transplant
- Johns Hopkins School of Nursing, Baltimore
Recruiting
Ages 18 to 99 · All sexes · Updated Jul 20, 2026 · NCT06326905CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
- Walter Reed National Medical Military Center, Bethesda
Recruiting
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05663034A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- Sheppard Pratt Health System, Inc., Baltimore
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
- Sheppard Pratt, Baltimore
- Sunstone Medical, PC, Rockville
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study
- Johns Hopkins University, Baltimore
Recruiting
Ages 18 and older · Women · Updated May 6, 2026 · NCT07227337VR-PMR for Post-Burn Symptoms
- Johns Hopkins Bayview Medical Center, Baltimore
Recruiting
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT07317271Glucose Variability and Cognition in Prediabetes
- Baltimore VA Geriatric Research Education and Clinical Center (GRECC), Baltimore
RecruitingObservational studyHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Mar 30, 2025 · NCT04201600From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.