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Esophageal Cancer clinical trials in Los Angeles, CA

15 studies for Esophageal Cancer are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • UCLA Department of Medicine-Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • Ronald Reagan UCLA Medical Center, Los Angeles
  • UCLA Department of Medicine-Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

RecruitingPhase 1/2
  • University of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

RecruitingPhase 3
  • UCLA, Los Angeles
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07217704

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • START - Los Angeles, Los Angeles
  • Cedars Sinai, Los Angeles
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

RecruitingPhase 1/2
  • UCLA Hematology/Oncology - Santa Monica ( Site 8905), Los Angeles
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06445972

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

RecruitingPhase 1/2
  • UCLA Hematology/Oncology - Santa Monica ( Site 6905), Los Angeles
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06469944

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • Ronald Reagan UCLA Medical Center, Los Angeles
  • The Regents of the University of California, Los Angeles
  • UCLA Department of Medicine-Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Recruiting
  • Oncology Institute for Hope and Innovation, Los Angeles
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 to 99 · All sexes · Updated Feb 20, 2026 · NCT04907643

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated Dec 11, 2025 · NCT06943521

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

RecruitingPhase 4
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 15, 2025 · NCT07124351

TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)

RecruitingObservational studyHealthy volunteers welcome
  • UCLA Medical Center, Los Angeles
Ages 18 to 100 · All sexes · Updated Feb 28, 2025 · NCT02634645

About Esophageal Cancer

Early esophageal cancer does not have symptoms. Factors that increase risk include heavy drinking and smoking. Learn how you can reduce your risk.

More about Esophageal Cancer on MedlinePlus

Esophageal Cancer trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.