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Cancer (all types) clinical trials in Los Angeles, CA

74 studies for Cancer (all types) are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

RecruitingPhase 3
  • Keck Medicine of USC, Los Angeles
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07195591

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Los Angeles
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)

RecruitingPhase 1/2
  • Children's Hospital Los Angeles ( Site 4006), Los Angeles
1 Month – 17 Years · All sexes · Updated Sep 25, 2026 · NCT07630974

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

RecruitingPhase 2/3
  • Cedars-Sinai Cancer at Cedars-Sinai Medical Center, Los Angeles
  • UCLA Department of Medicine - Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

RecruitingPhase 3
  • The Angeles Clinic and Research Institute, West Los Angeles Office, Los Angeles
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06901531

Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia

RecruitingPhase 3
  • Quetzal Site 7, Los Angeles
Ages 18 to 71 · All sexes · Updated Sep 23, 2026 · NCT07504458

Intratumoral N17350 in Advanced Solid Tumors

RecruitingPhase 1/2
  • The Angeles Clinic and Research Institute, Los Angeles
  • UCLA - Jonsson Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RecruitingPhase 2
  • The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate, Los Angeles
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

RecruitingPhase 1/2
  • Childrens Hospital Los Angeles ( Site 3006), Los Angeles
1 Month – 17 Years · All sexes · Updated Sep 17, 2026 · NCT06941272

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

RecruitingPhase 2
  • UCLA Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04996875

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

RecruitingPhase 1/2
  • University of Southern California /ID# 272414, Los Angeles
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06953960

A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

RecruitingPhase 1/2
  • University of Southern California Norris Comprehensive, Los Angeles
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06634589

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • USC/Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

RecruitingPhase 1/2
  • California Research Institute, Los Angeles
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05386108

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • USC/Norris Comprehensive Cancer Center, Los Angeles
  • University of California, Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

RecruitingPhase 3
  • Los Angeles Cancer Network, Los Angeles
  • Cedars-Sinai Cancer at Cedars-Sinai Medical Facility, Los Angeles
  • Los Angeles Cancer Network_Century City, Los Angeles
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Lurbinectedin in FET-Fused Tumors

RecruitingPhase 1/2
  • Cedars-Sinai Medical Center, Los Angeles
Ages 10 and older · All sexes · Updated Sep 2, 2026 · NCT05918640

Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

RecruitingObservational studyHealthy volunteers welcome
  • University of California, Los Angeles (Data or Specimen Analysis Only), Los Angeles
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07030686

A Study of ARC-02 in B-cell NHL

RecruitingPhase 1
  • Start Cala, Los Angeles
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07691606

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

RecruitingPhase 1
  • UCLA, Los Angeles
  • Valkyrie Clinical Trials, Los Angeles
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07321106

Effect of Meal Timing During Adjuvant Treatment for Cancer

Recruiting
  • Cedars Sinai Medical Center (CSMC), Los Angeles
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07524218

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Children's Hospital Los Angeles, Los Angeles
  • Cedars-Sinai Medical Center, Los Angeles
  • Mattel Children's Hospital UCLA, Los Angeles
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Abatacept in Immune Checkpoint Inhibitor Myocarditis

RecruitingPhase 3
  • Cedars-Sinai Medical Center, Los Angeles
  • University of California Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05335928

Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Site 03, Los Angeles
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07276373

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of California, Los Angeles (UCLA), Los Angeles
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

NLP-Based Feedback to Improve Risk Comms and Informed Shared Decision Making

Recruiting
  • Cedars-Sinai Medical Center, Los Angeles
Ages 18 and older · Men · Updated Aug 12, 2026 · NCT05923684

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

RecruitingPhase 1
  • START Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06880549

International Rare Brain Tumor Registry

RecruitingObservational study
  • Children's Hospital Los Angeles, Los Angeles
Up to age 45 · All sexes · Updated Aug 7, 2026 · NCT05697874

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

RecruitingPhase 2
  • UCLA Medical Center, Los Angeles
Ages 1 to 39 · All sexes · Updated Aug 7, 2026 · NCT05999994

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Kaiser Permanente Los Angeles Medical Center, Los Angeles
  • Kaiser Permanente West Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

RecruitingPhase 2
  • Cedars Sinai Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06417190

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

RecruitingPhase 2
  • Children's Hospital Los Angeles, Los Angeles
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • California Research Institute, Los Angeles
  • Valkyrie Clinical Trials, Los Angeles
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer

RecruitingHealthy volunteers welcome
  • Children's Hospital Los Angeles, Los Angeles
All ages · All sexes · Updated Jul 17, 2026 · NCT05294302

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • The Angeles Clinic and Research Institute, Los Angeles
Ages 12 and older · All sexes · Updated Jul 14, 2026 · NCT05533697

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Ellison Clinic at Saint John's, Los Angeles
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

The STOP-MED CTRCD Trial

RecruitingPhase 4
  • University of California, Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06183437

Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

RecruitingPhase 2
  • UCLA Department of Medicine, Los Angeles
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07216443

EXoPERT EMERALD Clinical Study

RecruitingObservational studyHealthy volunteers welcome
  • City of Hope Duarte Cancer Center, Los Angeles
Ages 45 and older · All sexes · Updated Jul 1, 2026 · NCT07186296

Molecular Genetics Studies of Cancer Patients and Their Relatives

RecruitingObservational studyHealthy volunteers welcome
  • USC / Norris Comprehensive Cancer Center, Los Angeles
All ages · All sexes · Updated Jun 29, 2026 · NCT04185935

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

RecruitingPhase 1
  • University of California, Los Angeles (UCLA) Department of Medicine - Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT04678648

Childhood Cancer Survivor Study

RecruitingObservational studyHealthy volunteers welcome
  • Children's Hospital Los Angeles, Los Angeles
  • University of California-Los Angeles, Los Angeles
All ages · All sexes · Updated Jun 17, 2026 · NCT01120353

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • UCLA Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

RecruitingPhase 1/2
  • The Angeles Clinic and Research Institute, Los Angeles
Ages 18 to 70 · All sexes · Updated Jun 11, 2026 · NCT05361174

LIFE Cancer Survivorship Database for Pediatric Cancer

RecruitingObservational study
  • Children's Hospital Los Angeles, Los Angeles
All ages · All sexes · Updated Jun 4, 2026 · NCT01518400

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

RecruitingHealthy volunteers welcome
  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Ages 13 to 30 · All sexes · Updated May 11, 2026 · NCT04453072

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

RecruitingPhase 2
  • University of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Recruiting
  • Oncology Institute for Hope and Innovation, Los Angeles
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

Norris ORIEN Total Cancer Care

RecruitingObservational study
  • USC / Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT02970045

Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

RecruitingObservational studyHealthy volunteers welcome
  • USC / Norris Comprehensive Cancer Center, Los Angeles
Ages 19 and older · All sexes · Updated Apr 2, 2026 · NCT03207854

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05948865

A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)

RecruitingPhase 1/2
  • Los Angeles General Medical Center, Los Angeles
  • USC/Norris Comprehensive Cancer Center, Los Angeles
Ages 18 to 99 · All sexes · Updated Mar 10, 2026 · NCT04333706

GEMINI-NSCLC: NSCLC Biomarker Study

RecruitingObservational study
  • UCLA, Los Angeles
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer

RecruitingObservational study
  • Jonsson Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT02280161

eMOTION: Examining Implicit Attitudes in Physical Activity Engagement

RecruitingObservational studyHealthy volunteers welcome
  • Univeristy of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated Nov 3, 2025 · NCT07044570

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

RecruitingPhase 1
  • USC Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT05808634

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • UCLA Medical Center, Los Angeles
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT06682793

A Study of NX-1607 in Adults With Advanced Malignancies

RecruitingPhase 1
  • University of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy

Recruiting
  • Cedars-Sinai Medical Center (CSMC), Los Angeles
  • University of California Los Angeles, Los Angeles
Ages 18 and older · All sexes · Updated Aug 14, 2025 · NCT04442724

Effects of Using a Storybook, to Explain Leukemia to Children Versus the Standard Child Life Intervention, on Parental Stress.

RecruitingHealthy volunteers welcome
  • Children's Hospital Los Angeles, Los Angeles
Ages 3 and older · All sexes · Updated Aug 3, 2025 · NCT06360718

eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

RecruitingHealthy volunteers welcome
  • University of Southern California, Los Angeles
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT06570642

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

RecruitingObservational study
  • University of Southern California - Norris Comprehensive Cancer Center, Los Angeles
Ages 18 and older · All sexes · Updated Jun 25, 2025 · NCT05768269

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • UCLA Health, Los Angeles
Ages 18 and older · All sexes · Updated May 18, 2025 · NCT05970497

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

RecruitingPhase 1/2
  • University of California, Los Angles (UCLA) Department of Medicine - Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated May 1, 2025 · NCT04503265

Trial of DFP-14927 in Advanced Solid Tumors

RecruitingPhase 1
  • UCLA Department of Medicine- Hematology/Oncology, Los Angeles
Ages 18 and older · All sexes · Updated Mar 3, 2025 · NCT03943004

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

RecruitingPhase 1/2
  • The Angeles Clinic and Research Institute, Los Angeles
Ages 18 and older · All sexes · Updated Feb 13, 2025 · NCT05669430

Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment

RecruitingObservational studyHealthy volunteers welcome
  • MiraKind, Los Angeles
Ages 18 and older · All sexes · Updated Jan 23, 2025 · NCT02253251

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • Los Angeles General Medical Center, Los Angeles
  • Los Angeles General Medical Center, Los Angeles
  • USC Norris Comprehensive Cancer Center, Los Angeles
  • and 2 more
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

RecruitingPhase 4
  • VA Greater Los Angeles Healthcare System, Los Angeles
Ages 18 and older · Men · Updated Nov 27, 2024 · NCT06706921

About Cancer (all types)

If you or someone you love has been diagnosed with cancer, learn about diagnosis, treatment, risk factors, coping and much more.

More about Cancer (all types) on MedlinePlus

Cancer (all types) trials in other cities

Other studies in Los Angeles

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.